Easy and Efficient Microwave-Assisted Synthesis of 1,2,3-Triazolyl-Tethered 2-Pyridinylbenzimidiazoles and Their Antimicrobial Activity

被引：1

作者：

Vishnuvardhan, M. ^{[1
]}

Pradeep, M. ^{[1
]}

Gangadhar, T. ^{[1
]}

机构：

[1] Osmania Univ, Dept Chem, Nat Prod Lab, Hyderabad 500007, Telangana, India

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 58卷 / 04期

关键词：

1; 2; 3-triazole; 2-pyridylbenzimidazole; microwave irradiation; click reaction; antimicrobial activity; BIOLOGICAL EVALUATION; BENZIMIDAZOLE; DERIVATIVES; ANTICONVULSANT;

D O I：

10.1134/S1070428022040182

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel 1,2,3-triazole-tethered 2-pyridinylbenzimidazole derivatives have been synthesized form 2-(pyridine-3-yl)benzimidazole under microwave irradiation. The microwave-assisted method proved to be simple and easy-to-perform and provided high yields within a short time. The structure of the synthesized compounds was confirmed by different spectroscopic techniques such as IR, H-1 and C-13 NMR, and mass spectrometry. The synthesized compounds were screened for their antimicrobial activity against four bacterial strains and two fungal strains.

引用

页码：592 / 596

页数：5

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