Therapeutic efficacy of nanomedicines for prostate cancer: An update

被引：17

作者：

Lakshmanan, Vinoth-Kumar ^{[1
]}

机构：

[1] Chonnam Natl Univ, Sch Med, Dept Biomed Sci, 160 Baekseo Ro, Gwangju 61469, South Korea

来源：

INVESTIGATIVE AND CLINICAL UROLOGY | 2016年 / 57卷 / 01期

关键词：

Diagnosis; Drug delivery systems; Nanomedicine; Prostate neoplasms; Therapy; DRUG-DELIVERY; TARGETED DELIVERY; IN-VITRO; POLYMERIC NANOPARTICLES; MAGNETIC NANOPARTICLES; GOLD NANOPARTICLES; PLGA NANOPARTICLES; CARBON NANOTUBES; RECEPTOR; DOCETAXEL;

D O I：

10.4111/icu.2016.57.1.21

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Recent advances in cancer nanomedicine have attracted remarkable attention in medical sectors. Pharmacologic research on nanomedicines, including targeted cancer therapy, has increased dramatically in the past 5 years. The success stories of nanomedicines in the clinical field include the fabrication of nanomedicines that show maximum loading efficiency into carriers, maximal release kinetics, and minimum toxicity to healthy cells. Nanoparticle-mediated medicines have been developed to specifically target prostate cancer tissue by use of aptamers, antibody targeting, and sustained release of nanomedicines in a dose-and time-dependent manner. Nanomedicines have been developed for therapeutic application in combination with image-guided therapy in real time. The scope of one of these nanomedicines, Abraxane (paclitaxel), may be extended to prostate cancer therapeutic applications for better quality of patient life and longer survival. This review provides an update on the latest directions and developments in nanomedicines for prostate cancer.

引用

页码：21 / 29

页数：9

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