Model of human cardiovascular system with a loop of autonomic regulation of the mean arterial pressure

被引：30

作者：

Karavaev, Anatoly S. ^{[1
]}

Ishbulatov, Yurii M. ^{[1
]}

Ponomarenko, Vladimir I. ^{[1
]}

Prokhorov, Mikhail D. ^{[1
]}

Gridnev, Vladimir I. ^{[2
]}

Bezruchko, Boris P. ^{[1
]}

Kiselev, Anton R. ^{[2
,3
]}

机构：

[1] Russian Acad Sci, Inst Radio Engn & Elect, Saratov Branch, Saratov, Russia

[2] Saratov State Med Univ, Cardiol Res Inst, Dept New Cardiol Informat Technol, Saratov, Russia

[3] Bakulev Sci Ctr Cardiovasc Surg, Dept Surg Treatment Interact Pathol, Moscow, Russia

来源：

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION | 2016年 / 10卷 / 03期

基金：

俄罗斯科学基金会;

关键词：

Arterial pressure; autonomic regulation; baroreflex; cardiovascular system; HEART-RATE-VARIABILITY; BLOOD-PRESSURE; 0.1-HZ OSCILLATIONS; RR-INTERVAL; FREQUENCY; RHYTHMS;

D O I：

10.1016/j.jash.2015.12.014

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

A model of human cardiovascular system is proposed which describes the main heart rhythm, the regulation of heart function and blood vessels by the autonomic nervous system, baroreflex, and the formation of arterial blood pressure. The model takes into account the impact of respiration on these processes. It is shown that taking into account nonlinearity and introducing the autonomous loop of mean arterial blood pressure in the form of self-oscillating time-delay system allow to obtain the model signals whose statistical and spectral characteristics are qualitatively and quantitatively similar to those for experimental signals. The proposed model demonstrates the phenomenon of synchronization of mean arterial pressure regulatory system by the signal of respiration with the basic period close to 10 seconds, which is observed in the physiological experiments. (C) 2016 American Society of Hypertension. All rights reserved.

引用

页码：235 / 243

页数：9

共 25 条

[21] Bifurcations in a nonlinear model of the baroreceptor-cardiac reflex [J].

Seidel, H ;

Herzel, H .

PHYSICA D, 1998, 115 (1-2) :145-162

[22] Mathematical modeling of cardiovascular coupling: Central autonomic commands and baroreflex control [J].

Silvani, Alessandro ;

Magosso, Elisa ;

Bastianini, Stefano ;

Lenzi, Pierluigi ;

Ursino, Mauro .

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 2011, 162 (1-2) :66-71

[23] Effects of Bilateral Stellate Ganglion Block on Autonomic Cardiovascular Regulation [J].

Song, Jun-Gol ;

Hwang, Gyu-Sam ;

Lee, Eun Ho ;

Leem, Jeong Gil ;

Lee, Chung ;

Park, Pyung Hwan ;

Shin, Jin Woo .

CIRCULATION JOURNAL, 2009, 73 (10) :1909-1913

[24] Fundamental relations between short-term RR interval and arterial pressure oscillations in humans [J].

Taylor, JA ;

Eckberg, DL .

CIRCULATION, 1996, 93 (08) :1527-1532

[25] THE FREQUENCY-DEPENDENT NATURE OF BLOOD PRESSURE REGULATION BY THE CAROTID SINUS STUDIED WITH AN ELECTRIC ANALOG [J].

WARNER, HR .

CIRCULATION RESEARCH, 1958, 6 (01) :35-40

← 1 2 3 →