Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy

被引:3
作者
Li, Yingxin [1 ,2 ]
Sallam, Karim [1 ,2 ]
Schwartz, Peter J. [3 ]
Wu, Joseph C. [1 ,2 ]
机构
[1] Stanford Univ, Sch Med, Stanford Cardiovasc Inst, Dept Med,Inst Stem Cell Biol & Regenerat Med, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Stanford Cardiovasc Inst, Dept Radiol,Inst Stem Cell Biol & Regenerat Med, Stanford, CA 94305 USA
[3] IRCCS, Ist Auxol Italiano, Ctr Cardiac Arrhythmias Genet Origin, Milan, Italy
基金
美国国家卫生研究院;
关键词
Editorials; cardiovascular diseases; induced pluripotent stem cells; myocytes; cardiac; ryanodine receptor calcium release channel; stem cells;
D O I
10.1161/CIRCEP.117.005398
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页数:3
相关论文
共 21 条
[1]  
Ben Jehuda Ronen, 2016, J Atr Fibrillation, V9, P1423, DOI 10.4022/jafib.1423
[2]  
Burridge PW, 2014, NAT METHODS, V11, P855, DOI [10.1038/NMETH.2999, 10.1038/nmeth.2999]
[3]   A New Initiative on Precision Medicine [J].
Collins, Francis S. ;
Varmus, Harold .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (09) :793-795
[4]   Clinical Management of Catecholaminergic Polymorphic Ventricular Tachycardia The Role of Left Cardiac Sympathetic Denervation [J].
De Ferrari, Gaetano M. ;
Dusi, Veronica ;
Spazzolini, Carla ;
Bos, J. Martijn ;
Abrams, Dominic J. ;
Berul, Charles I. ;
Crotti, Lia ;
Davis, Andrew M. ;
Eldar, Michael ;
Kharlap, Maria ;
Khoury, Asaad ;
Krahn, Andrew D. ;
Leenhardt, Antoine ;
Moir, Christopher R. ;
Odero, Attilio ;
Olde Nordkamp, Louise ;
Paul, Thomas ;
Roses i Noguer, Ferran ;
Shkolnikova, Maria ;
Till, Jan ;
Wilde, Arthur A. M. ;
Ackerman, Michael J. ;
Schwartz, Peter J. .
CIRCULATION, 2015, 131 (25) :2185-2193
[5]   Integrating Human Pluripotent Stem Cells into Drug Development [J].
Engle, Sandra J. ;
Puppala, Dinesh .
CELL STEM CELL, 2013, 12 (06) :669-677
[6]   Incidence and Risk Factors of Arrhythmic Events in Catecholaminergic Polymorphic Ventricular Tachycardia [J].
Hayashi, Meiso ;
Denjoy, Isabelle ;
Extramiana, Fabrice ;
Maltret, Alice ;
Buisson, Nathalie Roux ;
Lupoglazoff, Jean-Marc ;
Klug, Didier ;
Hayashi, Miyuki ;
Takatsuki, Seiji ;
Villain, Elisabeth ;
Kamblock, Joel ;
Messali, Anne ;
Guicheney, Pascale ;
Lunardi, Joel ;
Leenhardt, Antoine .
CIRCULATION, 2009, 119 (18) :2426-2434
[7]   Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Insights Into Molecular, Cellular, and Functional Phenotypes [J].
Karakikes, Ioannis ;
Ameen, Mohamed ;
Termglinchan, Vittavat ;
Wu, Joseph C. .
CIRCULATION RESEARCH, 2015, 117 (01) :80-88
[8]   Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome [J].
Liang, Ping ;
Sallam, Karim ;
Wu, Haodi ;
Li, Yingxin ;
Itzhaki, Ilanit ;
Garg, Priyanka ;
Zhang, Ying ;
Vermglinchan, Vittavat ;
Lan, Feng ;
Gu, Mingxia ;
Gong, Tingyu ;
Yan Zhuge ;
He, Chunjiang ;
Ebert, Antje D. ;
Sanchez-Freire, Veronica ;
Churko, Jared ;
Hu, Shijun ;
Sharma, Arun ;
Lam, Chi Keung ;
Scheinman, Melvin M. ;
Bers, Donald M. ;
Wu, Joseph C. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 68 (19) :2086-2096
[9]   Patient-Specific Drug Screening Using a Human Induced Pluripotent Stem Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Type 2 [J].
Maizels, Leonid ;
Huber, Irit ;
Arbel, Gil ;
Tijsen, Anke J. ;
Gepstein, Amira ;
Khoury, Asaad ;
Gepstein, Lior .
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2017, 10 (06)
[10]   Stem cells: disease models that show and tell [J].
Marx, Vivien .
NATURE METHODS, 2015, 12 (02) :111-114