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Neutropenia and renal dysfunction due to intravesical cidofovir for virus-associated hemorrhagic cystitis after kidney and allogenic hematopoietic stem cell transplantations
被引:5
作者:
Shimizu, Takuya
[1
]
Kondo, Tadakazu
[1
]
Matsumoto, Kana
[2
]
Hishizawa, Masakatsu
[1
]
Yamashita, Kouhei
[1
]
Takaori-Kondo, Akifumi
[1
]
机构:
[1] Kyoto Univ, Grad Sch Med, Dept Hematol & Oncol, Kyoto, Japan
[2] Doshisha Womens Coll Liberal Arts, Fac Pharmaceut Sci, Dept Clin Pharmaceut, Kyoto, Japan
关键词:
allogenic hematopoietic stem cell transplantation;
cidofovir;
intravesical;
kidney transplantation;
virus-associated hemorrhagic cystitis;
GUIDELINES;
D O I:
10.1111/tid.13185
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
We present a patient with virus-associated hemorrhagic cystitis who underwent kidney and allogenic hematopoietic stem cell transplantations (allo-HSCT). Six months post-allo-HSCT, adenovirus hemorrhagic cystitis occurred, which has been in remission after a single dose of intravesical cidofovir. This might cause prolonged neutropenia and nephrotoxicity, suggesting cidofovir absorption in the blood.
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页数:4
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