Neutropenia and renal dysfunction due to intravesical cidofovir for virus-associated hemorrhagic cystitis after kidney and allogenic hematopoietic stem cell transplantations

被引：6

作者：

Shimizu, Takuya ^{[1
]}

Kondo, Tadakazu ^{[1
]}

Matsumoto, Kana ^{[2
]}

Hishizawa, Masakatsu ^{[1
]}

Yamashita, Kouhei ^{[1
]}

Takaori-Kondo, Akifumi ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Hematol & Oncol, Kyoto, Japan

[2] Doshisha Womens Coll Liberal Arts, Fac Pharmaceut Sci, Dept Clin Pharmaceut, Kyoto, Japan

来源：

TRANSPLANT INFECTIOUS DISEASE | 2019年 / 21卷 / 06期

关键词：

allogenic hematopoietic stem cell transplantation; cidofovir; intravesical; kidney transplantation; virus-associated hemorrhagic cystitis; GUIDELINES;

D O I：

10.1111/tid.13185

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We present a patient with virus-associated hemorrhagic cystitis who underwent kidney and allogenic hematopoietic stem cell transplantations (allo-HSCT). Six months post-allo-HSCT, adenovirus hemorrhagic cystitis occurred, which has been in remission after a single dose of intravesical cidofovir. This might cause prolonged neutropenia and nephrotoxicity, suggesting cidofovir absorption in the blood.

引用

页数：4

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