The synthesis of (4S,5S)-(-)-isocytoxazone

被引：4

作者：

Rozwadowska, Maria D. ^{[1
]}

Tomczak, Anna ^{[1
]}

机构：

[1] Adam Mickiewicz Univ Poznan, Fac Chem, PL-60780 Poznan, Poland

来源：

TETRAHEDRON-ASYMMETRY | 2009年 / 20卷 / 17期

关键词：

STEREOSELECTIVE-SYNTHESIS; ABSOLUTE-CONFIGURATION; CYTOKINE MODULATOR; CYTOXAZONE; ALCOHOLS;

D O I：

10.1016/j.tetasy.2009.07.034

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(4S,5S)-(-)-Isocytoxazone, which is needed for a configurational study, was synthesized from the commercially available (1S,2S)-(+)-2-amino-1-(4-nitrophenyl)-1,3-propanediolin which the p-nitro substituent was replaced by a p-methoxyl group; the thus prepared p-methoxyphenyl amino diol was cyclized via an N-Boc derivative. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2048 / 2051

页数：4

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