The synthesis of (4S,5S)-(-)-isocytoxazone

被引：4
|
作者：
Rozwadowska, Maria D. [1 ]
Tomczak, Anna [1 ]
机构：
[1] Adam Mickiewicz Univ Poznan, Fac Chem, PL-60780 Poznan, Poland
来源：
TETRAHEDRON-ASYMMETRY | 2009年 / 20卷 / 17期
关键词：
STEREOSELECTIVE-SYNTHESIS; ABSOLUTE-CONFIGURATION; CYTOKINE MODULATOR; CYTOXAZONE; ALCOHOLS;
D O I：
10.1016/j.tetasy.2009.07.034
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
(4S,5S)-(-)-Isocytoxazone, which is needed for a configurational study, was synthesized from the commercially available (1S,2S)-(+)-2-amino-1-(4-nitrophenyl)-1,3-propanediolin which the p-nitro substituent was replaced by a p-methoxyl group; the thus prepared p-methoxyphenyl amino diol was cyclized via an N-Boc derivative. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2048 / 2051
页数：4
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