SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW DIHYDROPYRIDINE, PYRAZOLE, CHROMENE, PYRROLE, THIAZOLE AND THIOPHENE DERIVATIVES

被引：6
|
作者：
Fadda, Ahmed A. [1 ]
Refat, Hala M. [2 ]
Mohamed, Khaled S. [3 ]
Mohamed, Nada A. H. [1 ]
机构：
[1] Mansoura Univ, Fac Sci, Dept Chem, Mansoura 35516, Egypt
[2] Suez Canal Univ, Fac Educ, Dept Chem, Al Arish 45511, Egypt
[3] Higher Inst Engn & Technol, Dept Chem Engn, New Damietta, Egypt
来源：
HETEROCYCLES | 2014年 / 89卷 / 10期
关键词：
HETEROCYCLIC SYNTHESIS; HYDRAZIDE-HYDRAZONES; ACID; NITRILES; PYRIDINE; UTILITY; DESIGN;
D O I：
10.3987/COM-14-13072
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Synthesis of 2-cyano-N((2-methoxynaphthalen-1-yl)methylene)acetohydrazide (3) and its use as a key intermediate for the synthesis of some new heterocyclic compounds such as dihydropyridines (4, 6 and 8), pyrazoles (9 and 10), chromene (11), pyrroles (12 and 13), thiazoles (14 and 17) and thiophene (18-20) derivatives were described. The structures of newly synthesized compounds have been established on the basis of their IR, H-1-NMR, C-13-NMR and mass spectral data and have been screened for their antimicrobial activity.
引用
收藏
页码：2318 / 2333
页数：16
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