SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW DIHYDROPYRIDINE, PYRAZOLE, CHROMENE, PYRROLE, THIAZOLE AND THIOPHENE DERIVATIVES

被引：6

作者：

Fadda, Ahmed A. ^{[1
]}

Refat, Hala M. ^{[2
]}

Mohamed, Khaled S. ^{[3
]}

Mohamed, Nada A. H. ^{[1
]}

机构：

[1] Mansoura Univ, Fac Sci, Dept Chem, Mansoura 35516, Egypt

[2] Suez Canal Univ, Fac Educ, Dept Chem, Al Arish 45511, Egypt

[3] Higher Inst Engn & Technol, Dept Chem Engn, New Damietta, Egypt

来源：

HETEROCYCLES | 2014年 / 89卷 / 10期

关键词：

HETEROCYCLIC SYNTHESIS; HYDRAZIDE-HYDRAZONES; ACID; NITRILES; PYRIDINE; UTILITY; DESIGN;

D O I：

10.3987/COM-14-13072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of 2-cyano-N((2-methoxynaphthalen-1-yl)methylene)acetohydrazide (3) and its use as a key intermediate for the synthesis of some new heterocyclic compounds such as dihydropyridines (4, 6 and 8), pyrazoles (9 and 10), chromene (11), pyrroles (12 and 13), thiazoles (14 and 17) and thiophene (18-20) derivatives were described. The structures of newly synthesized compounds have been established on the basis of their IR, H-1-NMR, C-13-NMR and mass spectral data and have been screened for their antimicrobial activity.

引用

页码：2318 / 2333

页数：16

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