A facile one-pot three-component synthesis of benzylideneamino-3,5-dimethyl-1H-pyrazoles

被引:5
|
作者
Jilloju, Parameshwara Chary [1 ]
Vedula, Rajeswar Rao [1 ]
机构
[1] Natl Inst Technol, Dept Chem, Warangal, Telangana, India
关键词
4-Amino-5-hydrazinyl-4H-1,2,4-triazole-3-thiol; acetyl acetone; 3; 5-dimethyl-1H-pyrazole; three-component; PYRAZOLE DERIVATIVES; SCHIFF-BASES; ANTIBACTERIAL; AGENTS; TRIAZOLOTHIADIAZINES; FLUORINE;
D O I
10.1080/00397911.2018.1458242
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile, one-pot three-component protocol for the synthesis of substituted 4-(benzylideneamino)-5-(3,5-dimethyl-1H-pyrazol-1-yl)-4H-1,2,4-triazole-3-thiols have been reported by the reaction of 4-amino-5-hydrazinyl-4H-1,2,4-triazole-3-thiol with acetyl acetone and various substituted benzaldehydes via multi component reaction. The newly synthesized derivatives were characterized by their elemental analysis and spectral data. The current strategy provides heterocyclic compounds in good yields with broad substrate scope. [GRAPHICS] .
引用
收藏
页码:1739 / 1746
页数:8
相关论文
共 50 条
  • [21] Synthesis of quinoline-based glycoconjugates: a facile one-pot three-component reaction
    Kumar, K. Karthik
    Das, Thangamuthu Mohan
    CARBOHYDRATE RESEARCH, 2011, 346 (06) : 728 - 732
  • [22] Efficient Three-Component One-Pot Synthesis of 4H-Pyrans
    J. Malviya
    S. Kala
    L. K. Sharma
    R. K. P. Singh
    Russian Journal of Organic Chemistry, 2019, 55 : 686 - 693
  • [23] Efficient Three-Component One-Pot Synthesis of 4H-Pyrans
    Malviya, J.
    Kala, S.
    Sharma, L. K.
    Singh, R. K. P.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 55 (05) : 686 - 693
  • [24] An Efficient One-Pot Synthesis of 3,5-Disubstituted 1H-Pyrazoles
    Wu, Lei-Lei
    Ge, Yi-Cen
    He, Ting
    Zhang, Lei
    Fu, Xing-Li
    Fu, Hai-Yan
    Chen, Hua
    Li, Rui-Xiang
    SYNTHESIS-STUTTGART, 2012, 44 (10): : 1577 - 1583
  • [25] FACILE, ONE-POT, THREE-COMPONENT SYNTHESIS OF BENZO[a]NAPHTHACENE-8,13-DIONES
    Srinivas, Vakiti
    Rao, Vedula Rajeswar
    SYNTHETIC COMMUNICATIONS, 2012, 42 (03) : 388 - 393
  • [26] Three-component one-pot reaction for the synthesis of β-amide ketones
    Luo, Yan-Ping
    Chen, Qiong
    CHEMICAL PAPERS, 2013, 67 (05) : 532 - 537
  • [27] A Photochemical One-Pot Three-Component Synthesis of Tetrasubstituted Imidazoles
    Pusch, Stefan
    Opatz, Till
    ORGANIC LETTERS, 2014, 16 (20) : 5430 - 5433
  • [28] One-pot three-component reaction for the synthesis of α-(aminoethyl)-α,β-enones
    Bertozzi, F
    Gustafsson, M
    Olsson, R
    ORGANIC LETTERS, 2002, 4 (24) : 4333 - 4336
  • [29] AN EFFICIENT THREE-COMPONENT ONE-POT SYNTHESIS OF PYRIMIDOBENZIMIDAZOLE DERIVATIVES
    Kumar, Goda Pankaja
    Sekhar, Thuraka
    Thriveni, Pinnu
    Venkateswarlu, Annavarapu
    Reddy, Peduri Suresh
    HETEROCYCLIC LETTERS, 2021, 11 (02): : 231 - 236
  • [30] One-pot, three-component synthesis of arylidenesuccinates and related compounds
    McCombie, SW
    Luchaco, CA
    TETRAHEDRON LETTERS, 1997, 38 (33) : 5775 - 5776