Nanomaterials for the Delivery of Herbal Bioactive Compounds

被引:14
作者
Wahab, Shadma [1 ]
Ahmad, Md. Parwez [2 ]
Hussain, Arshad [3 ]
Qadir, Shaik Fayazuddin Abdul [1 ]
机构
[1] King Khalid Univ, Dept Pharmacognosy, Coll Pharm, Abha, Saudi Arabia
[2] Mald Natl Univ, Sch Med, Dept Pharmacol, Mate, Maldives
[3] Harsha Inst Pharm, Dept Pharm, Lucknow, Uttar Pradesh, India
关键词
Nanomaterial; herbal bioactive; drug delivery; nanocarrier; liposomes; niosomes; phytosomes; hydrogels; dendrimers; nanoparticles; micelles; nanoemulsion; DRUG-DELIVERY; IN-VITRO; GREEN TEA; PHOSPHOLIPID COMPLEX; POLYMERIC MICELLES; CHINESE MEDICINE; TOPICAL DELIVERY; BIOAVAILABILITY; CANCER; FORMULATION;
D O I
10.2174/1573413717666211004090341
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nanotechnology is a multidisciplinary domain that involves overlapping areas such as nanomaterials, nanoelectronics, and nanobiotechnology. Herbal medicine is a significant component of traditional medicine and has been a part of treating many diseases. Asian people have been using these herbal medicines for decades. Still, herbal extracts' therapeutic efficacy and pharmaceutical application are associated with many factors such as poor bioavailability, low solubility, permeability, and lack of targeting potential. In the present work, we have reviewed thriving strategies for the targeted drug delivery of phytoconstituents and critically explained the most recent progressions on emerging novel nano-phytomedicine-based materials as herbal medicines carriers. Nanotechnology-based clinical trial studies targeting herbal bioactive compounds were discussed. Advancements in nanotechnology-based drug delivery systems intended to enhance cellular uptake, improved pharmacokinetics, and effectiveness of herbal drugs have facilitated the powerful targeting of specific agents against diseases. This review provides insight into the current progress and future opportunities for nanomedicines as potential curative targets for the delivery of herbal bioactive compounds. This information could be used as a platform for the future expansion of multi-functional nano constructs for the advanced detection of diseases and functional drug delivery of phytoconstituents.
引用
收藏
页码:425 / 441
页数:17
相关论文
共 50 条
  • [41] NANOMATERIALS FOR PROTEIN-MEDIATED THERAPY AND DELIVERY
    Barry, John N.
    Vertegel, Alexey A.
    NANO LIFE, 2013, 3 (04)
  • [42] Emerging novel drug delivery strategies for bioactive flavonol fisetin in biomedicine
    Mehta, Piyush
    Pawar, Atmaram
    Mahadik, Kakasaheb
    Bothiraja, C.
    BIOMEDICINE & PHARMACOTHERAPY, 2018, 106 : 1282 - 1291
  • [43] Current Development and Application on Inclusion of Herbal Phytochemicals in Novel Herbal Drug Delivery System
    Ahmed, Aziz
    Ahmad, Rizwan
    Jangir, Shurbhi
    Sharma, Deeksha
    NATURAL PRODUCTS JOURNAL, 2025, 15 (01) : 24 - 35
  • [44] Lignin as a Natural Carrier for the Efficient Delivery of Bioactive Compounds: From Waste to Health
    Verdini, Federico
    Gaudino, Emanuela Calcio
    Canova, Erica
    Tabasso, Silvia
    Behbahani, Paria Jafari
    Cravotto, Giancarlo
    MOLECULES, 2022, 27 (11):
  • [45] Marine-Derived Polysaccharide Hydrogels as Delivery Platforms for Natural Bioactive Compounds
    Sepe, Fabrizia
    Valentino, Anna
    Marcolongo, Loredana
    Petillo, Orsolina
    Conte, Raffaele
    Margarucci, Sabrina
    Peluso, Gianfranco
    Calarco, Anna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2025, 26 (02)
  • [46] Self-Emulsifying Systems for Delivery of Bioactive Compounds from Natural Origin
    de Oliveira, Mariana Carla
    Bruschi, Marcos Luciano
    AAPS PHARMSCITECH, 2022, 23 (05)
  • [47] Bioactive compounds: Application of albumin nanocarriers as delivery systems
    Visentini, Flavia F.
    Perez, Adrian A.
    Santiago, Liliana G.
    CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2023, 63 (25) : 7238 - 7268
  • [48] Bioactive Compounds Formulated in Phytosomes Administered as Complementary Therapy for Metabolic Disorders
    Toma, Laura
    Deleanu, Mariana
    Sanda, Gabriela Maria
    Barbalata, Teodora
    Niculescu, Loredan Stefan
    Sima, Anca Volumnia
    Stancu, Camelia Sorina
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (08)
  • [49] A Comprehensive Review on Niosomes as a Strategy in Targeted Drug Delivery: Pharmaceutical, and Herbal Cosmetic Applications
    Saharawat, Sakshi
    Verma, Sushma
    CURRENT DRUG DELIVERY, 2024, 21 (11) : 1460 - 1473
  • [50] Stimuli-Responsive Polymeric Nanomaterials for the Delivery of Immunotherapy Moieties: Antigens, Adjuvants and Agonists
    Nagareddy, Raveena
    Thomas, Reju George
    Jeong, Yong Yeon
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (22)