Nanomaterials for the Delivery of Herbal Bioactive Compounds

被引:14
|
作者
Wahab, Shadma [1 ]
Ahmad, Md. Parwez [2 ]
Hussain, Arshad [3 ]
Qadir, Shaik Fayazuddin Abdul [1 ]
机构
[1] King Khalid Univ, Dept Pharmacognosy, Coll Pharm, Abha, Saudi Arabia
[2] Mald Natl Univ, Sch Med, Dept Pharmacol, Mate, Maldives
[3] Harsha Inst Pharm, Dept Pharm, Lucknow, Uttar Pradesh, India
关键词
Nanomaterial; herbal bioactive; drug delivery; nanocarrier; liposomes; niosomes; phytosomes; hydrogels; dendrimers; nanoparticles; micelles; nanoemulsion; DRUG-DELIVERY; IN-VITRO; GREEN TEA; PHOSPHOLIPID COMPLEX; POLYMERIC MICELLES; CHINESE MEDICINE; TOPICAL DELIVERY; BIOAVAILABILITY; CANCER; FORMULATION;
D O I
10.2174/1573413717666211004090341
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nanotechnology is a multidisciplinary domain that involves overlapping areas such as nanomaterials, nanoelectronics, and nanobiotechnology. Herbal medicine is a significant component of traditional medicine and has been a part of treating many diseases. Asian people have been using these herbal medicines for decades. Still, herbal extracts' therapeutic efficacy and pharmaceutical application are associated with many factors such as poor bioavailability, low solubility, permeability, and lack of targeting potential. In the present work, we have reviewed thriving strategies for the targeted drug delivery of phytoconstituents and critically explained the most recent progressions on emerging novel nano-phytomedicine-based materials as herbal medicines carriers. Nanotechnology-based clinical trial studies targeting herbal bioactive compounds were discussed. Advancements in nanotechnology-based drug delivery systems intended to enhance cellular uptake, improved pharmacokinetics, and effectiveness of herbal drugs have facilitated the powerful targeting of specific agents against diseases. This review provides insight into the current progress and future opportunities for nanomedicines as potential curative targets for the delivery of herbal bioactive compounds. This information could be used as a platform for the future expansion of multi-functional nano constructs for the advanced detection of diseases and functional drug delivery of phytoconstituents.
引用
收藏
页码:425 / 441
页数:17
相关论文
共 50 条
  • [1] Hydrogel: An Encouraging Nanocarrier System for the Delivery of Herbal Bioactive Compounds
    Wahab, Shadma
    Ahmad, Irfan
    Irfan, Safia
    Ahmad, Md Faruque
    Usmani, Shazia
    Shoaib, Ambreen
    Ahmad, Wasim
    CURRENT NANOSCIENCE, 2021, 17 (06) : 797 - 807
  • [2] Nanomaterials of Natural Bioactive Compounds for Wound Healing: Novel Drug Delivery Approach
    Kant, Vinay
    Kumari, Pooja
    Jitendra, Dhaval K.
    Ahuja, Munish
    Kumar, Vinod
    CURRENT DRUG DELIVERY, 2021, 18 (10) : 1406 - 1425
  • [3] Advanced Targeted Drug Delivery of Bioactive Nanomaterials in the Management of Cancer
    Basu, Biswajit
    Garala, Kevin
    Patel, Rajeshri
    Dutta, Ayon
    Ash, Dipanjana
    Prajapati, Bhupendra
    Singh, Sudarshan
    Jha, Sajal Kumar
    CURRENT MEDICINAL CHEMISTRY, 2024,
  • [4] The role of nanomaterials in cell delivery systems
    Golchin, Ali
    Hosseinzadeh, Simzar
    Roshangar, Leila
    MEDICAL MOLECULAR MORPHOLOGY, 2018, 51 (01) : 1 - 12
  • [5] Nanomedicine-based approaches for delivery of herbal compounds
    Kumar, Virender
    Garg, Vandana
    Dureja, Harish
    TRADITIONAL MEDICINE RESEARCH, 2022, 7 (05):
  • [6] Recent advances in protein-based nanoparticles and their applications in the delivery of bioactive compounds
    Saif, Asifa
    Anjum, Laiba
    Faisal, Zargham
    Akram, Noor
    Shah, Yasir Abbas
    Irfan, Rushba
    Saeed, Farhan
    Afzaal, Muhammad
    Asif Shah, Mohd
    INTERNATIONAL JOURNAL OF FOOD PROPERTIES, 2023, 26 (02) : 2881 - 2895
  • [7] Colloidal and vesicular delivery system for herbal bioactive constituents
    Pandey, Ravindra
    Bhairam, Monika
    Shukla, Shiv Shankar
    Gidwani, Bina
    DARU-JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 29 (02) : 415 - 438
  • [8] Nanostructured Lipid Carriers for the Delivery of Natural Bioactive Compounds
    Shamsuddin, Nur Amira Mohd
    Zulfakar, Mohd. Hanif
    CURRENT DRUG DELIVERY, 2023, 20 (02) : 127 - 143
  • [9] Phytosomes: a critical tool for delivery of herbal drugs for cancer
    Chaudhary, Kajal
    Rajora, Anjali
    PHYTOCHEMISTRY REVIEWS, 2024, 24 (1) : 165 - 195
  • [10] Design, Synthesis, and Functionalization of Nanomaterials for Therapeutic Drug Delivery
    Grandhi, Taraka Sai Pavan
    Rege, Kaushal
    NANOMATERIAL: IMPACTS ON CELL BIOLOGY AND MEDICINE, 2014, 811 : 157 - 182