Self-renewal and differentiation in squamous cell carcinomas

被引：0
作者：
Sastre-Perona, Ana [1 ]
Hoang-Phou, Steven [1 ]
Schober, Markus [1 ]
机构：
[1] NYU, Sch Med, Ronald O Perelman Dept Dermatol, 550 1St Ave, New York, NY 10016 USA
来源：
AGING-US | 2019年 / 11卷 / 20期
关键词：
PITX1; SOX2; KLF4; cancer stem cells; transcriptional networks; self-renewal; squamous cell carcinoma; SOX2;
D O I：
10.18632/aging.102381
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：8736 / 8738
页数：3
相关论文
共 8 条
  • [1] Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice
    Adam, Rene C.
    Yang, Hanseul
    Rockowitz, Shira
    Larsen, Samantha B.
    Nikolova, Maria
    Oristian, Daniel S.
    Polak, Lisa
    Kadaja, Meelis
    Asare, Amma
    Zheng, Deyou
    Fuchs, Elaine
    [J]. NATURE, 2015, 521 (7552) : 366 - +
  • [2] SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
    Boumahdi, Soufiane
    Driessens, Gregory
    Lapouge, Gaelle
    Rorive, Sandrine
    Nassar, Dany
    Le Mercier, Marie
    Delatte, Benjamin
    Caauwe, Amelie
    Lenglez, Sandrine
    Nkusi, Erwin
    Brohee, Sylvain
    Salmon, Isabelle
    Dubois, Christine
    del Marmol, Veronique
    Fuks, Francois
    Beck, Benjamin
    Blanpain, Cedric
    [J]. NATURE, 2014, 511 (7508) : 246 - +
  • [3] Stem Cell Lineage Infidelity Drives Wound Repair and Cancer
    Ge, Yejing
    Gomez, Nicholas C.
    Adam, Rene C.
    Nikolova, Maria
    Yang, Hanseul
    Verma, Akanksha
    Lu, Catherine Pei-Ju
    Polak, Lisa
    Yuan, Shaopeng
    Elemento, Olivier
    Fuchs, Elaine
    [J]. CELL, 2017, 169 (04) : 636 - 650
  • [4] Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
    Latil, Mathilde
    Nassar, Dany
    Beck, Benjamin
    Boumahdi, Soufiane
    Wang, Li
    Brisebarre, Audrey
    Dubois, Christine
    Nkusi, Erwin
    Lenglez, Sandrine
    Checinska, Agnieszka
    Drubbel, Alizee Vercauteren
    Devos, Michael
    Declercq, Wim
    Yi, Rui
    Blanpain, Cedric
    [J]. CELL STEM CELL, 2017, 20 (02) : 191 - +
  • [5] De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma
    Sastre-Perona, Ana
    Hoang-Phou, Steven
    Leitner, Marie-Christin
    Okuniewska, Martyna
    Meehan, Shane
    Schober, Markus
    [J]. CELL STEM CELL, 2019, 24 (03) : 390 - +
  • [6] Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling
    Schober, Markus
    Fuchs, Elaine
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (26) : 10544 - 10549
  • [7] SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma
    Siegle, Jasmin M.
    Basin, Alice
    Sastre-Perona, Ana
    Yonekubo, Yoshiya
    Brown, Jessie
    Sennett, Rachel
    Rendl, Michael
    Tsirigos, Aristotelis
    Carucci, John A.
    Schober, Markus
    [J]. NATURE COMMUNICATIONS, 2014, 5
  • [8] ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas
    Yang, Hanseul
    Schramek, Daniel
    Adam, Rene C.
    Keyes, Brice E.
    Wang, Ping
    Zheng, Deyou
    Fuchs, Elaine
    [J]. ELIFE, 2015, 4
1