Malignant fibrous histiocytoma:: An ultrastructural perspective

被引:0
作者
Suh, CH [1 ]
Ordóñez, NG [1 ]
Mackay, B [1 ]
机构
[1] Chosun Univ, Dept Pathol, Kwangju 501759, South Korea
关键词
electron microscopy; fibrosarcoma; immunohistochemistry; malignant fibrous histiocytoma; soft tissue tumors;
D O I
暂无
中图分类号
TH742 [显微镜];
学科分类号
摘要
Malignant fibrous histiocytoma is a frequent diagnosis, but the relationship of the tumors to histologically similar soft tissue neoplasms is controversial. In this study, 157 examples representing the 4 main subtypes were reviewed by light microscopy and each tumor was studied with the electron microscope. Immunohistochemical stains were performed on 77 tumors. Electron micrographs on 100 fibrosarcomas were reviewed for comparison. Malignant fibrous histiocytomas often closely resemble fibrosarcomas at the ultrastructural level and differences between the two are generally of degree only. Evidence for true histiocytic differentiation was not found. The immunohistochemical results did not contradict the authors' impression from electron microscopy that malignant fibrous histiocytoma forms part of the histologic spectrum of tumors of fibroblasts.
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页码:243 / 250
页数:8
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