Reaction-Based Fluorescent Probes for the Imaging of Nitroxyl (HNO) in Biological Systems

被引：41
作者：
Dong, Baoli [1 ]
Kong, Xiuqi [1 ]
Lin, Weiying [1 ]
机构：
[1] Univ Jinan, Sch Mat Sci & Engn, Sch Chem & Chem Engn, Inst Fluorescent Probes Biol Imaging, Jinan 250022, Shandong, Peoples R China
来源：
ACS CHEMICAL BIOLOGY | 2018年 / 13卷 / 07期
关键词：
LIVING CELLS; NITRIC-OXIDE; IN-VIVO; REDUCTANT-RESISTANT; AQUEOUS-SOLUTION; TISSUES; COMPLEX; DISCRIMINATION; VISUALIZATION; MITOCHONDRIA;
D O I：
10.1021/acschembio.7b00901
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Nitroxyl (HNO) has been identified as an important signaling molecule in biological systems and plays critical roles in many physiological processes. Fluorescence imaging could provide a robust approach to explore the biological formation of HNO and its physiological functions. Herein, we summarize the organic reaction types for constructing HNO probes and specifically focus on review of the recent advances in the development of the reaction-based HNO probes and their imaging applications in living systems.
引用
收藏
页码：1714 / 1720
页数：7
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