Changes in fat-free mass during significant weight loss: a systematic review

被引:328
作者
Chaston, T. B. [1 ]
Dixon, J. B. [1 ]
O'Brien, P. E. [1 ]
机构
[1] Monash Univ, Sch Med, Alfred Hosp, Australian Obes Res & Educ, Melbourne, Vic 3004, Australia
关键词
body composition; dual x-ray absorptiometry; under water weighing; total body water;
D O I
10.1038/sj.ijo.0803483
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To identify the proportion of weight lost as fat-free mass (FFM) by various weight loss interventions. Methods: Medline and Embase were systematically searched for reliable measurements of FFM before and after weight loss of 410 kg and eligible data were pooled. In a fixed effect model of % FFM loss/weight loss (% FFML), linear regression analysis was used to determine the influence of degree of caloric restriction, exercise, magnitude of weight loss, initial body mass index (BMI) and type of surgery. Results: Data were included from 26 cohorts treated with dietary and behavioral interventions and 29 cohorts of bariatric surgery patients. The degree of caloric restriction was positively associated with % FFML (r(2) = 0.31, P = 0.006) and in three randomized controlled trials exercise was shown to decrease % FFML. Compared with laparoscopic adjustable gastric banding (LAGB), biliopancreatic diversion (BPD) and roux en Y gastric bypass (RYGB) caused greater log(e) (natural log) % FFML (r(2) = 0.453, P < 0.001). Differences in log(e) % FFML between surgical procedures were independent of initial BMI and magnitude of weight loss. Conclusions: The degree of caloric restriction, exercise and rate of weight loss influence the proportion of weight lost as FFM after non-surgical interventions. For surgical interventions, BPD and RYGB result in greater % FFML than LAGB.
引用
收藏
页码:743 / 750
页数:8
相关论文
共 63 条
  • [1] Exercise and diet in obesity treatment: An integrative system dynamics perspective
    Abdel-Hamid, TK
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2003, 35 (03) : 400 - 414
  • [2] ALOIA JF, 1995, J NUCL MED, V36, P1392
  • [3] Body composition and energy expenditure after weight loss following bariatric surgery
    Benedetti, G
    Mingrone, G
    Marcoccia, S
    Benedetti, M
    Giancaterini, A
    Greco, AV
    Castagneto, M
    Gasbarrini, G
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2000, 19 (02) : 270 - 274
  • [4] Obesity treatment with a progressive clinical tri-therapy combining sibutramine and a supervised diet-exercise intervention
    Bérubé-Parent, S
    Prud'homme, D
    St-Pierre, S
    Doucet, E
    Tremblay, A
    [J]. INTERNATIONAL JOURNAL OF OBESITY, 2001, 25 (08) : 1144 - 1153
  • [5] Validation of air-displacement plethysmography for estimation of body fat mass in healthy elderly subjects
    Bosy-Westhal, A
    Mast, M
    Eichhorn, C
    Becker, C
    Kutzner, D
    Heller, M
    Müller, MJ
    [J]. EUROPEAN JOURNAL OF NUTRITION, 2003, 42 (04) : 207 - 216
  • [6] Bariatric surgery: A systematic review and meta-analysis
    Buchwald, H
    Avidor, Y
    Braunwald, E
    Jensen, MD
    Pories, W
    Fahrbach, K
    Schoelles, K
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (14): : 1724 - 1737
  • [7] CAMPBELL JN, 1989, TXB PAIN, V2, P22
  • [8] Carey DG, 2006, OBES SURG, V16, P469
  • [9] One-year changes in energy expenditure and serum leptin following adjustable gastric banding in obese women
    Coupaye, M
    Bouillot, JL
    Coussieu, C
    Guy-Grand, B
    Basdevant, A
    Oppert, JM
    [J]. OBESITY SURGERY, 2005, 15 (06) : 827 - 833
  • [10] Accuracy of bioelectrical impedance spectroscopy in measuring changes in body composition during severe weight loss
    Cox-Reijven, PLM
    van Kreel, B
    Soeters, PB
    [J]. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 2002, 26 (02) : 120 - 127