Effect of probiotics on body weight and body-mass index: a systematic review and meta-analysis of randomized, controlled trials

被引：87

作者：

Zhang, Qingqing ^{[1
]}

Wu, Yucheng ^{[2
]}

Fei, Xiaoqiang ^{[1
]}

机构：

[1] Taizhou Peoples Hosp, Dept Endocrinol, Taizhou 225300, Jiangsu, Peoples R China

[2] Taizhou Peoples Hosp, Dept Cardiol, Taizhou 225300, Jiangsu, Peoples R China

来源：

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION | 2016年 / 67卷 / 05期

关键词：

BMI; meta-analysis; obesity; overweight; probiotics; LACTOBACILLUS-GASSERI SBT2055; ALTERED GUT MICROBIOTA; BLOOD-PRESSURE; DOUBLE-BLIND; ABDOMINAL ADIPOSITY; YOGURT CONSUMPTION; LIPID PROFILE; UNITED-STATES; RISK-FACTORS; OBESE;

D O I：

10.1080/09637486.2016.1181156

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Objective: To assess the efficacy of probiotic therapies on body weight and BMI using a meta-analysis of randomized, controlled trials.Methods: Twenty studies with 25 trials (1931 participants with age over 18 years) were included. The pooled WMD was calculated by random effects model.Results: Probiotic consumption significantly reduced body weight by 0.59kg (95% CI, 0.30-0.87) and BMI by 0.49kg/m(2) (95% CI, 0.24-0.74). A greater reduction in BMI was found with multiple species of probiotics. Subgroup analysis of trials with intervention duration 8 weeks found a more significant reduction in BMI. Limiting analysis to trials with a baseline BMI 25kg/m(2) showed a greater reduction in BMI.Conclusion: Consuming probiotics could reduce body weight and BMI, with a potentially greater effect when multiple species of probiotics were consumed, the duration of intervention was 8 weeks, or the objects were overweight.

引用

页码：571 / 580

页数：10

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