Prognostic value of hypoxia-regulated gene expression in loco-regional gastroesophageal cancer

被引:3
作者
Winther, M. [1 ]
Alsner, J. [1 ]
Tramm, T. [2 ]
Holtved, E. [3 ]
Baeksgaard, L. [4 ]
Nordsmark, M. [5 ]
机构
[1] Aarhus Univ Hosp, Dept Expt Clin Oncol, Noerrebrogade 44,Bldg 5, DK-8000 Aarhus, Denmark
[2] Aarhus Univ Hosp, Dept Pathol, DK-8000 Aarhus, Denmark
[3] Odense Univ Hosp, Dept Oncol, DK-5000 Odense, Denmark
[4] Rigshosp, Dept Oncol, DK-2100 Copenhagen, Denmark
[5] Aarhus Univ Hosp, Dept Oncol, DK-8000 Aarhus, Denmark
关键词
RADIATION-THERAPY; CLASSIFIER; IMPACT; HEAD; NECK; RADIOTHERAPY;
D O I
10.3109/0284186X.2015.1114680
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:652 / 655
页数:4
相关论文
共 10 条
[1]   HYPOXIA AND METABOLISM SERIES - TIMELINE The impact of O2 availability on human cancer [J].
Bertout, Jessica A. ;
Patel, Shetal A. ;
Simon, M. Celeste .
NATURE REVIEWS CANCER, 2008, 8 (12) :967-975
[2]   Gene Expression Signatures as Biomarkers of Tumour Hypoxia [J].
Harris, B. H. L. ;
Barberis, A. ;
West, C. M. L. ;
Buffa, F. M. .
CLINICAL ONCOLOGY, 2015, 27 (10) :547-560
[3]   Hypoxia and anemia: Factors in decreased sensitivity to radiation therapy and chemotherapy? [J].
Harrison, L ;
Blackwell, K .
ONCOLOGIST, 2004, 9 :31-40
[4]  
Hockel M, 1996, CANCER RES, V56, P4509
[5]   Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study [J].
Nordsmark, M ;
Bentzen, SM ;
Rudat, V ;
Brizel, D ;
Lartigau, E ;
Stadler, P ;
Becker, A ;
Adam, M ;
Molls, M ;
Dunst, J ;
Terriis, DJ ;
Overgaard, J .
RADIOTHERAPY AND ONCOLOGY, 2005, 77 (01) :18-24
[6]   The usability of a 15-gene hypoxia classifier as a universal hypoxia profile in various cancer cell types [J].
Sorensen, Brita Singers ;
Knudsen, Anders ;
Wittrup, Catja Foged ;
Nielsen, Steffen ;
Aggerholm-Pedersen, Ninna ;
Busk, Morten ;
Horsman, Michael ;
Hoyer, Morten ;
Bouchelouche, Pierre Nourdine ;
Overgaard, Jens ;
Alsner, Jan .
RADIOTHERAPY AND ONCOLOGY, 2015, 116 (03) :346-351
[7]   Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck [J].
Toustrup, Kasper ;
Sorensen, Brita Singers ;
Lassen, Pernille ;
Wiuf, Carsten ;
Alsner, Jan ;
Overgaard, Jens .
RADIOTHERAPY AND ONCOLOGY, 2012, 102 (01) :122-129
[8]   Development of a Hypoxia Gene Expression Classifier with Predictive Impact for Hypoxic Modification of Radiotherapy in Head and Neck Cancer [J].
Toustrup, Kasper ;
Sorensen, Brita Singers ;
Nordsmark, Marianne ;
Busk, Morten ;
Wiuf, Carsten ;
Alsner, Jan ;
Overgaard, Jens .
CANCER RESEARCH, 2011, 71 (17) :5923-5931
[9]   Hypoxia in cancer: significance and impact on clinical outcome [J].
Vaupel, Peter ;
Mayer, Arnulf .
CANCER AND METASTASIS REVIEWS, 2007, 26 (02) :225-239
[10]   Hypoxia-regulated gene expression and prognosis in loco-regional gastroesophageal cancer [J].
Winther, Mette ;
Alsner, Jan ;
Tramm, Trine ;
Nordsmark, Marianne .
ACTA ONCOLOGICA, 2013, 52 (07) :1327-1335