Probiotics and prebiotics in Crohn's disease therapies

被引:41
作者
Lichtenstein, Lev [1 ,2 ]
Avni-Biron, Irit [1 ,2 ]
Ben-Bassat, Ofer [1 ,2 ]
机构
[1] Rabin Med Ctr, IL-4941492 Petah Tilcva, Israel
[2] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
关键词
Probiotics; Prebiotics; Synbiotics; Inflammatory bowel disease; Crohn's disease; VSL#3; Sacchromyces boullardi; Bifidobacterium; Lactobacillus; INFLAMMATORY-BOWEL-DISEASE; POSTOPERATIVE RECURRENCE; LACTOBACILLUS-GG; SACCHAROMYCES-BOULARDII; DOUBLE-BLIND; MAINTAINING REMISSION; ENDOSCOPIC RECURRENCE; MAINTENANCE THERAPY; ULCERATIVE-COLITIS; CONTROLLED TRIAL;
D O I
10.1016/j.bpg.2016.02.002
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Therapeutic manipulation of gut microbiota has proven valuable in the management of ulcerative colitis and pouchitis. Despite some similarities among the various inflammatory bowel conditions, the probiotics investigated thus far seem to confer little benefit in Crohn's disease. In this review, we aim to bring together the evidence available on the clinical effect of probiotics and prebioltics in Crohn's disease patients, and to clarify the place of probiotic treatment in current Crohn's therapeutic regimens. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:81 / 88
页数:8
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