Perianal Hodgkin's lymphoma complicating Crohn's disease

被引：8

作者：

Sivarajasingham, N ^{[1
]}

Adams, SA

Smith, MEF

Hosie, KB

机构：

[1] Derriford Hosp, Dept Surg, Plymouth PL6 8DH, Devon, England

[2] Derriford Hosp, Dept Histopathol, Plymouth PL6 8DH, Devon, England

来源：

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE | 2003年 / 18卷 / 02期

关键词：

Crohn's disease; Hodgkin's lymphoma; idiopathic inflammatory bowel disease; perianal disease;

D O I：

10.1007/s00384-002-0448-x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: The perianal region is a very rare location for Hodgkin's lymphoma, and clinicians may often neglect the diagnosis in patients with inflammatory bowel disease. Patient presentation: We present a case of perianal Hodgkin's lymphoma in patient with Crohn's disease who was on long-term immunosuppression and whose symptoms would normally be attributed to Crohn's disease. Diagnosis was based on the morphological appearance of atypical cells in the lamina propria and the immunohistochemical profile of Reed Sternberg and Hodgkin's cells, showing coexpression of CD15 and CD30. Conclusion: Perianal complaints in patients with inflammatory bowel disease may be a manifestation of other pathology. Hodgkin's lymphoma could be a progression in the chronically inflamed tissue in this unusual location.

引用

页码：174 / 176

页数：3

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