Synthesis and characterization of three new organo-selenium compounds. A convenient synthesis of aroylselenoglycolic acids

被引：14

作者：

de Athayde, PF ^{[1
]}

de Souza, AG

de Morais, SA

Botelho, JR

Barbosa, JM

Miller, J

Lira, BF

机构：

[1] Univ Fed Paraiba, Dept Quim, CCEN, BR-58081970 Joao Pessoa, Paraiba, Brazil

[2] Univ Fed Paraiba, Lab Tecnol Farmaceut, BR-58081970 Joao Pessoa, Paraiba, Brazil

[3] Univ Fed Paraiba, Dept Quim Fundamental, BR-58081970 Joao Pessoa, Paraiba, Brazil

来源：

ARKIVOC | 2004年

关键词：

organo-selenium; one-pot synthesis; aroylselenoglycolic acids;

D O I：

10.3998/ark.5550190.0005.604

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient one-pot three stage synthesis has been developed and used for obtaining three new aroylselenoglycolic acids. In the first stage powdered grey selenium reacts with NaBH4 in aqueous solution to form NaHSe. This reacts with selected aroyl chlorides to form sodium aroylselenides. In the third stage these react with alpha-chloroacetic acid to form the desired aroylselenoglycolic acids. They were characterized by IR, H-1 and C-13 NMR spectrometry and by Elemental Analysis.

引用

页码：22 / 26

页数：5

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