In vivo monitoring of bone-Pb and retrospective exposure: an assessment in occupationally exposed subjects

被引:3
作者
Tartari, A
Casnati, E
Baraldi, C
Giganti, M
De Rosa, E
Gregorio, P
Brito, J
机构
[1] Univ Ferrara, Dipartimento Fis, I-44100 Ferrara, Italy
[2] Univ Ferrara, Dipartimento Med Clin & Sperimentale, I-44100 Ferrara, Italy
[3] Univ Ferrara, Ist Igiene & Med Lavoro, I-44100 Ferrara, Italy
[4] Univ Lisbon, Ctr Fis Atom, P-1699 Lisbon, Portugal
关键词
bone lead; X-ray fluorescence; occupational exposure; protoporphyrine;
D O I
10.1016/S0946-672X(97)80051-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this work we present the preliminary results of an investigation in to the bone burden of lead in occupationally exposed subjects. The assessment of bone lead levels normalised to the mineral content (mg/kg bone mineral) were carried out by means of an in vivo X ray fluorescence techniques (Pb-XRF). The measurements were performed on the second phalanx of the right index finger and the minimum detectable limits of the XRF techniques was estimated around 25-30 mg/kg. Although the blood lead level monitoring over long time seems to indicate working activities in environments with low sources of lead contamination, high Pb-XRF levels, and not well correlated with the exposure time, were found. These anomalous values could be explained in term of the dependence of zinc protoporphyrin assessment against the measurement time.
引用
收藏
页码:179 / 181
页数:3
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