Association of IGF-1 with coronary collateral circulation in stable coronary artery disease

被引:7
作者
Kundi, Harun [1 ]
Gok, Murat [1 ]
Kiziltunc, Emrullah [1 ]
Cetin, Mustafa [1 ]
Ornek, Ender [1 ]
机构
[1] Ankara Numune Training & Res Hosp, Cardiol Dept, Ankara, Turkey
关键词
coronary collateral circulation; hs-CRP; inflammation; IGF-1; stable coronary artery disease; C-REACTIVE PROTEIN; GROWTH-FACTOR-I; CARDIOVASCULAR RISK-FACTORS; HEART-DISEASE; BINDING PROTEIN-1; ELEVATED LEVELS; ISCHEMIA; ATHEROSCLEROSIS; POPULATION; OCCLUSION;
D O I
10.2217/bmm-2016-0354
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Aim: The aim of the present study is to evaluate the relationship between coronary collateral circulation (CCC) grade and serum IGF-1 levels in patients diagnosed with stable coronary artery disease. Methods: Totally, 190 consecutive patients with stable coronary artery disease who underwent coronary angiography were included in this study. Results: The patients with good CCC had significantly higher IGF-1 levels compared with the poor ones. On the contrary, hs-CRP was significantly lower in the good CCC group. We also demonstrated that IGF-1 level was significantly related with the grade of CCC. Conclusion: We believe that measurement of IGF-1 level may help clinicians for predicting CCC development.
引用
收藏
页码:527 / 534
页数:8
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