E1 on the move

被引:2
作者
VanDemark, AP [1 ]
Hill, CP [1 ]
机构
[1] Univ Utah, Sch Med, Dept Biochem, Salt Lake City, UT 84132 USA
关键词
D O I
10.1016/j.molcel.2005.02.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
E1 enzymes activate ubiquitin or related proteins and pass them to E2 enzymes. A recent structure and associated biochemical studies (Huang et al., 2005) show how an E1 binds its cognate E2 and indicates that large, conformational changes will be an integral component of the E1 reaction cycle.
引用
收藏
页码:474 / 475
页数:2
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