Postoperative radiotherapy in non-small-cell lung cancer: update of an individual patient data meta-analysis

被引：121

作者：

Burdett, S ^{[1
]}

Stewart, L ^{[1
]}

机构：

[1] Meta Anal Grp, MRC Clin Trials Unit, London NW1 2DA, England

来源：

LUNG CANCER | 2005年 / 47卷 / 01期

关键词：

meta-analysis; non-small cell lung cancer; radiotherapy; surgery;

D O I：

10.1016/j.lungcan.2004.09.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report an updated systematic review and individual patient data meta-analysis of the effectiveness of postoperative radiotherapy (PORT) in nonsmall-cell lung cancer. Results continue to show PORT to be detrimental, with an 18% relative increase in the risk of death. Similar detriments Were observed for local recurrence-free survival, distant recurrence-free survival and overall recurrence-free survival. There continues to be evidence that the effects of PORT are more harmful in those patients with stage I disease than those with stage 11 disease. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

引用

页码：81 / 83

页数：3

共 3 条

[1]

Burdett S, 1998, LANCET, V352, P257

[2]

*PORT MET AN TRIAL, 2000, POST RAD NON SMALL C

[3] Adjuvant radiotherapy in non-small cell lung cancer with pathological stage I: definitive results of a phase III randomized trial [J].

Trodella, L ;

Granone, P ;

Valente, S ;

Valentini, V ;

Balducci, M ;

Mantini, G ;

Turriziani, A ;

Margaritora, S ;

Cesario, A ;

Ramella, S ;

Corbo, GM ;

D'Angelillo, RM ;

Fontana, A ;

Galetta, D ;

Cellini, N .

RADIOTHERAPY AND ONCOLOGY, 2002, 62 (01) :11-19

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