AmberliteTM IRA67: A novel and efficient ion exchange resin catalyst for the synthesis of 1, 8-dioxoxanthene derivatives

The catalytic performance of Amberlite(TM) IRA67, the heterogeneous weak Base Exchange resin which bears tertiary amine functional group, for the synthesis of 1, 8-dioxoxanthene derivatives were investigated. The Amberlite(TM) IRA67 heterogeneous resin catalyst was found to be efficient and easily recoverable in the reaction of aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione to their corresponding 1, 8-dioxoxanthene derivatives under novel reaction conditions. Short reaction times, excellent yields (88-98%) and simple experimental procedure with an easy work-up are some of the advantages of the procedure. A total of 11 new compounds have been synthesized with a variety of substituent. The characterization of the compounds was completed using melting point determination, FT-IR, H-1-NMR, and C-13-NMR spectroscopic methods. The Amberlite(TM) IRA67 catalyst could be easily recovered after reaction completion and reused six times with an excellent durability and without any noticeable loss in activity. Furthermore, this general and simple method may be of much significance in many of other catalytic applications. [GRAPHICS] .