Polymer monoliths synthesized by radiation co-polymerization in solution

被引：9

作者：

Beiler, Barbara ^{[1
]}

Safrany, Agnes ^{[1
]}

机构：

[1] Hungarian Acad Sci, Radiat Chem Dept, Inst Isotopes, H-1525 Budapest, Hungary

来源：

RADIATION PHYSICS AND CHEMISTRY | 2007年 / 76卷 / 8-9期

基金：

匈牙利科学研究基金会;

关键词：

synthetic polymers; radiation polymerization and cross-linking; porous monoliths; chromatography; separation;

D O I：

10.1016/j.radphyschem.2007.02.030

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Hydrophilic co-polymer monoliths were prepared by irradiating alcoholic solutions containing diethyleneglycol dimethacrylate (DEGDMA) and 2-hydroxyethylacrylate (HEA) monomers. The effect of monomer ratio, solvent properties and radiation dose on the porous properties of the monoliths was studied in detail and compared to the monolith prepared from DEGDMA. Increase of the HEA content in the co-monomer mixture (up to 18 vol%) resulted in monoliths with increased pore size and hydrophilic character. The biggest pores were obtained when methanol was used as solvent. The use of the monoliths as chromatographic columns for separation of proteins, amino and nucleic acids is also reported. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1351 / 1354

页数：4

共 8 条

[1] From microspheres to monoliths:: Synthesis of porous supports with tailored properties by radiation polymerization [J].

Grasselli, M ;

Smolko, E ;

Hargittai, N ;

Sáfrány, A .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2001, 185 (1-4) :254-261

[2] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY ON CONTINUOUS POLYMER BEDS [J].

HJERTEN, S ;

LIAO, JL ;

ZHANG, R .

JOURNAL OF CHROMATOGRAPHY, 1989, 473 (01) :273-275

[3] PERFUSION CHROMATOGRAPHY [J].

REGNIER, FE .

NATURE, 1991, 350 (6319) :634-635

[4] Control of pore formation in macroporous polymers synthesized by single-step γ-radiation-initiated polymerization and cross-linking [J].

Sáfrány, A ;

Beiler, B ;

László, K ;

Svec, F .

POLYMER, 2005, 46 (09) :2862-2871

[5] CONTINUOUS RODS OF MACROPOROUS POLYMER AS HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY SEPARATION MEDIA [J].

SVEC, F ;

FRECHET, JMJ .

ANALYTICAL CHEMISTRY, 1992, 64 (07) :820-822

[6] New designs of macroporous polymers and supports: From separation to biocatalysis [J].

Svec, F ;

Frechet, JMJ .

SCIENCE, 1996, 273 (5272) :205-211

[7] Monolithic materials - Promises, challenges, achievements [J].

Svec, F ;

Huber, CG .

ANALYTICAL CHEMISTRY, 2006, 78 (07) :2100-2107

[8]

Svec F., 2003, Monolithic materials: preparation, properties and applications, VVolume 67

← 1 →