Prevalence and trends of type 2 diabetes mellitus and prediabetes among community-dwelling heart failure patients in the United States

Aims: This study estimated national prevalence and trends of diagnosed and undiagnosed type 2 diabetes mellitus (T2DM) and prediabetes among heart failure (HF) patients in the U.S. Methods: This cross-sectional study included 527 participants aged 20+ years with a diagnosis of HF, using data from the National Health and Nutrition Examination Survey 2005 & ndash;2016. We assessed prevalence estimates of diagnosed and undiagnosed T2DM and prediabetes stratified by age-standardized sociodemographic and health characteristics. Trends of T2DM and prediabetes prevalence were examined using logistic regressions. Results: Prevalence rates of diagnosed and undiagnosed T2DM among HF patients were 34.7% (95% confidence interval (CI), 29.2 & ndash;40.3%) and 12.8% (95% CI, 9.2 & ndash;16.9%), respectively. Prediabetes affected 39.1% (95% CI, 33.6 & ndash;44.9%) of HF patients. Prevalence estimates of diagnosed T2DM were significantly different between non-Hispanic White (20.1% [95% CI, 13.5 & ndash;27.6%]) and Hispanic participants (52.1% [95% CI, 35.9 & ndash;68.0%]) (P < 0.001). The prevalence of T2DM and prediabetes did not significantly change between 2005 and 2016. Conclusions: Prevalence rates of T2DM and prediabetes among community-dwelling HF patients in the U.S. remained high between 2005 and 2016. Prevention of and targeted intervention for T2DM among at-risk HF patients is needed, particularly among those of Hispanic origin. (C) 2022 Elsevier B.V. All rights reserved.