Magnesium degradation under physiological conditions - Best practice

被引:237
作者
Gonzalez, Jorge [1 ]
Hou, Rui Qing [1 ]
Nidadavolu, Eshwara P. S. [1 ]
Willumeit-Roemer, Regine [1 ]
Feyerabend, Frank [1 ]
机构
[1] Helmholtz Zentrum Geesthacht, Div Metall Biomat, Inst Mat Res, Max Planck Str 1, D-21502 Geesthacht, Germany
关键词
In vitro; Flow conditions; Degradation products; Cell culture conditions; IN-VITRO DEGRADATION; SIMULATED BODY-FLUIDS; MODIFIED EAGLE MEDIUM; IRON RE-DEPOSITION; HIGH-PURITY MG; ZN-ZR ALLOYS; PURE MAGNESIUM; CORROSION BEHAVIOR; HANKS SOLUTION; HEPES BUFFER;
D O I
10.1016/j.bioactmat.2018.01.003
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This review focusses on the application of physiological conditions for the mechanistic understanding of magnesium degradation. Despite the undisputed relevance of simplified laboratory setups for alloy screening purposes, realistic and predictive in vitro setups are needed. Due to the complexity of these systems, the review gives an overview about technical measures, defines some caveats and can be used as a guideline for the establishment of harmonized laboratory approaches. (c) 2018 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
引用
收藏
页码:174 / 185
页数:12
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