Asthma exacerbation related to viral infections: An up to date summary

被引:28
作者
Adeli, Mehdi [1 ,2 ,3 ]
El-Shareif, Tamara [2 ]
Hendaus, Mohamed A. [1 ,2 ,3 ]
机构
[1] Sidra Med, Dept Pediat, Sect Acad Gen Pediat, Doha, Qatar
[2] Hamad Gen Corp, Dept Pediat, Doha, Qatar
[3] Weill Cornell Med, Dept Clin Pediat, Doha, Qatar
关键词
Asthma; exacerbations; pulmonary function; virus-induced asthma; NEAR-FATAL ASTHMA; RISK-FACTORS; RHINOVIRUS INFECTION; AIRWAY INFLAMMATION; SEASONAL RISK; VIRUS; OUTCOMES; CARE; EPIDEMIOLOGY; EOSINOPHILS;
D O I
10.4103/jfmpc.jfmpc_86_19
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Asthma exacerbation can be a major life threatening event. Viruses have been pinned as the cause behind the vast majority of these exacerbations. The purpose of this short review is to explore the mechanisms behind these exacerbations, focusing mostly on viral infections as triggers. We will also be discussing the phenotypes prone to asthma exacerbation, the pathophysiology of viral induced asthma and ventilation patterns of asthmatic lungs. This manuscript will assist primary care physicians in delineating the proper pathophysiology of the disease as well as the management.
引用
收藏
页码:2753 / 2759
页数:7
相关论文
共 80 条
  • [21] Toward Primary Prevention of Asthma Reviewing the Evidence for Early-Life Respiratory Viral Infections as Modifiable Risk Factors to Prevent Childhood Asthma
    Feldman, Amy S.
    He, Yuan
    Moore, Martin L.
    Hershenson, Marc B.
    Hartert, Tina V.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191 (01) : 34 - 44
  • [22] Rhinovirus-16 colds in healthy and in asthmatic subjects - Similar changes in upper and lower airways
    Fleming, HE
    Little, FF
    Schnurr, D
    Avila, PC
    Wong, H
    Liu, J
    Yagi, S
    Boushey, HA
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 160 (01) : 100 - 108
  • [23] Viral and bacterial infections in the development and progression of asthma
    Gern, JE
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 105 (02) : S497 - S502
  • [24] Counterregulation between the FcεRI Pathway and Antiviral Responses in Human Plasmacytoid Dendritic Cells
    Gill, Michelle A.
    Bajwa, Gagan
    George, Tiffany A.
    Dong, Caroline C.
    Dougherty, Irene I.
    Jiang, Nan
    Gan, Vanthaya N.
    Gruchalla, Rebecca S.
    [J]. JOURNAL OF IMMUNOLOGY, 2010, 184 (11) : 5999 - 6006
  • [25] The impact of asthma exacerbations and preventive strategies
    Graham, LeRoy M.
    Eid, Nemr
    [J]. CURRENT MEDICAL RESEARCH AND OPINION, 2015, 31 (04) : 825 - 835
  • [26] Interleukin-10 gene expression in acute virus-induced asthma
    Grissell, TV
    Powell, H
    Shafren, DR
    Boyle, MJ
    Hensley, MJ
    Jones, PD
    Whitehead, BF
    Gibson, PG
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 172 (04) : 433 - 439
  • [27] Nonpharmacologic Therapy for Severe Persistent Asthma
    Hall, Chase
    Nici, Linda
    Sood, Shweta
    ZuWallack, Richard
    Castro, Mario
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2017, 5 (04) : 928 - 935
  • [28] Rhinovirus and Asthma: a Storied History of Incompatibility
    Hammond, Catherine
    Kurten, Megan
    Kennedy, Joshua L.
    [J]. CURRENT ALLERGY AND ASTHMA REPORTS, 2015, 15 (02)
  • [29] Is ketamine a lifesaving agent in childhood acute severe asthma?
    Hendaus, Mohamed A.
    Jomha, Fatima A.
    Alhammadi, Ahmed H.
    [J]. THERAPEUTICS AND CLINICAL RISK MANAGEMENT, 2016, 12 : 273 - 279
  • [30] Late-onset asthma: current perspectives
    Hirano, Tsunahiko
    Matsunaga, Kazuto
    [J]. JOURNAL OF ASTHMA AND ALLERGY, 2018, 11 : 19 - 27