Use of 68Ga-FAPI PET/CT for Evaluation of Peritoneal Carcinomatosis Before and After Cytoreductive Surgery

被引：11
作者：
Zhao, Liang [1 ,2 ,3 ]
Pang, Yizhen [1 ,2 ]
Wei, Jihong [1 ,2 ]
Hao, Bing [1 ,2 ]
Chen, Haojun [1 ,2 ]
机构：
[1] Fujian Med Univ, Teaching Hosp, Xiamen Univ, Dept Nucl Med,Affiliated Hosp 1,Xiamen Canc Ctr, 55 Zhenhai Rd, Xiamen 361003, Peoples R China
[2] Fujian Med Univ, Teaching Hosp, Xiamen Univ, Minnan PET Ctr,Affiliated Hosp 1,Xiamen Canc Ctr, Xiamen, Peoples R China
[3] Fujian Med Univ, Teaching Hosp, Xiamen Univ, Dept Radiat Oncol,Xiamen Canc Ctr,Affiliated Hosp, Xiamen, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2021年 / 46卷 / 06期
关键词：
Ga-68-FAPI; F-18-FDG; peritoneal carcinomatosis; cytoreductive surgery; response evaluation;
D O I：
10.1097/RLU.0000000000003611
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 55-year-old woman underwent F-18-FDG and Ga-68-FAPI PET/CT for tumor detection and staging under the prospective study NCT04416165. Both scans showed a mass lesion with increased tracer uptake in the pancreas. Moreover, Ga-68-FAPI PET/CT showed a greater number of abnormal foci in the mesentery and omentum than that shown with F-18-FDG. These abnormal foci were suspected to be metastases from pancreatic cancer. The patient subsequently underwent a cytoreductive surgery, and postoperative histopathology confirmed the diagnosis of acinar cell carcinoma of pancreas. Follow-up Ga-68-FAPI PET/CT (3 months after surgery) showed an excellent response with decreasing Ga-68-FAPI activity in the whole abdomen.
引用
收藏
页码：491 / 493
页数：3
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