Prevalence and outcomes of malnutrition among hospitalized COVID-19 patients: A systematic review and meta-analysis

被引:56
作者
Abate, Semagn Mekonnen [1 ]
Chekole, Yigrem Ali [2 ]
Estifanos, Mahlet Birhane [3 ]
Abate, Kalkidan Hassen [4 ]
Kabthymer, Robel Hussen [3 ]
机构
[1] Dilla Univ, Coll Hlth Sci & Med, Dept Anesthesiol, Dilla, Ethiopia
[2] Dilla Univ, Coll Hlth Sci & Med, Dept Psychiat, Dilla, Ethiopia
[3] Dilla Univ, Coll Hlth Sci & Med, Sch Publ Hlth, Dept Nutr, Dilla, Ethiopia
[4] Jimma Univ, Coll Publ Hlth & Med Sci, Dept Nutr & Dietet, Jimma, Ethiopia
关键词
Malnutrition; Mortality; Prevalence; NUTRIC; COVID-19; ASSOCIATION; RISK;
D O I
10.1016/j.clnesp.2021.03.002
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background: Malnutrition is inevitable in patients with Coronavirus Disease 2019 (COVID-19) due to its effect on the gastrointestinal system, immune system, and high metabolic activity. However, the prevalence of malnutrition and its outcomes is uncertain. This study aimed to investigate the prevalence and outcome of malnutrition among patients with COVID-19. Method: A comprehensive search was conducted in PubMed/Medline; Science direct and LILACS from December 29, 2019 to September, 2020 without language restriction. All observational studies reporting the prevalence of malnutrition were included while case reports and reviews were excluded. The data were extracted with two independent authors with a customized format and the disagreements were resolved by the other authors. The methodological quality of included studies was evaluated using a standardized critical appraisal tool. Results: A total of 511 articles were identified from different databases and 27 articles were selected for evaluation after the successive screening. Fourteen articles with 4187 participants were included. The pooled prevalence of malnutrition among hospitalized patients with COVID-19 was 49.11% (95% CI: 31.67 to 66.54). The odd of mortality among patients COVID-19 with malnutrition was 10 times more likely as compared to those who were well-nourished. Conclusion: The prevalence of malnutrition and mortality associated with malnutrition among COVID-19 hospitalized patients was very high which entails a mitigating strategy by different stakeholders to prevent and manage malnutrition and its outcomes. Registration: This systematic review was registered in Prospero's international prospective register of systematic reviews (CRD42020215396). (C) 2021 The Author(s). Published by Elsevier Ltd on behalf of European Society for Clinical Nutrition and Metabolism.
引用
收藏
页码:174 / 183
页数:10
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