One-pot Negishi cross-coupling reaction of aryldiazonium salts via Ni catalysis induced by visible-light

Visible-light induced catalysis is of high interest for its mild and environmentally benign properties. Herein, a general Ni catalysis accelerated by visible-light was successfully developed for one-pot Negishi coupling reactions at room temperature in a short reaction time (<2 h), using diazonium salts with Ar2Zn generated in situ from Grignard reagents and ZnBr2. This protocol provides a convenient access to C-C bond formation for important biaryl components. It tolerates various functional groups, and Hammett study illuminates the possiblility of Ni(III)/Ni(I) redox catalytic cycle.