When the idea of a large space station in Low Earth Orbit (LEO) was conceived in the 1980s, it was primarily planned as an orbiting laboratory for microgravity research. Some even thought of it as an industrial plant in space. Whereas the latter did not materialize because of various reasons, the former is absolutely true when you talk about the International Space Station (ISS). Since the transition to a six astronaut crew in 2009 and the completion of its assembly in 2011, it has been intensively used as laboratory in a wide field of scientific topics. Experiments conducted on ISS have yielded first class results in biology, physiology, material science, basic physics, and many more. While its role as a laboratory in space is widely recognized, the awareness for its potential for preparing future exploration missions beyond LEO is just increasing. This paper provides information on how the ISS programme contributes to future exploration efforts, both manned and unmanned. It highlights the work that has been done or is currently underway in the fields of technology, operations, and science. Further potentials and future projects for exploration preparation are also shown. A special focus lies on experiments and projects primarily funded by the German Aerospace Center (DLR) or with strong German participation in the science team. (C) 2014 IAA. Published by Elsevier Ltd. All rights reserved.