Pd-Catalyzed Suzuki-Miyaura Cross-Coupling of Arylboronic Acids and -Iminonitriles through C-CN Bond Activation

被引：7

作者：

Liu, Kui ^{[1
]}

Tao, Shou-Wei ^{[1
]}

Qian, Chun ^{[1
]}

Zhu, Yong-Ming ^{[1
]}

机构：

[1] Soochow Univ, Coll Pharmaceut Sci, Suzhou 215123, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 2018卷 / 34期

关键词：

Cross-coupling; Cyanides; Ketones; Boron; Synthetic methods; Homogeneous catalysis; INTRAMOLECULAR AMINOCYANATION; ALPHA-IMINONITRILE; PALLADIUM; CLEAVAGE; ALKENES; ARYLCYANATION; ISOMERIZATION; CYANATION; COMPLEXES; ACYLATION;

D O I：

10.1002/ejoc.201800857

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Pd-catalyzed Suzuki-Miyaura cross-coupling reaction between arylboronic acids and -iminonitriles has been developed. The reaction proceeds through selective activation of the C-CN bond, tolerates a wide range of substituents, and delivers the versatile ketone products in moderate to excellent yields.

引用

页码：4769 / 4775

页数：7

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