Two-component signaling circuit structure and properties

被引:118
作者
Goulian, Mark [1 ]
机构
[1] Univ Penn, Dept Biol, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
BACTERIAL-CELL CYCLE; ESCHERICHIA-COLI; BACILLUS-SUBTILIS; REGULATORY SYSTEMS; TRANSDUCTION SYSTEM; RESPONSE REGULATOR; POSITIVE FEEDBACK; GENETIC CIRCUIT; CROSS-TALK; EXPRESSION;
D O I
10.1016/j.mib.2010.01.009
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Various modeling and experimental studies have analyzed the reactions, interconnections, and motifs in two-component systems, with an eye toward understanding their physiological implications and the differences between alternative designs. Examples where recent progress has been made include aspects of autoregulation, signal integration in branched pathways, cross-talk suppression, and cross-regulation via connector proteins.
引用
收藏
页码:184 / 189
页数:6
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