More is better: Lymph node harvesting in colorectal cancer

被引:13
作者
O'Boyle, Sean [1 ]
Stephenson, Keith [1 ]
机构
[1] Virginia Tech, Carilion Sch Med, Carilion Clin, Roanoke, VA 24016 USA
关键词
COLON-CANCER; OPEN COLECTOMY; STAGE-II; NUMBER; RESECTION; TRIAL;
D O I
10.1016/j.amjsurg.2017.03.012
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction: We sought to determine if lymph node harvesting and survival for CRC were comparable between laparoscopic and open resections in a community hospital setting. Methods: A retrospective chart review of patients at two community hospitals who underwent open or laparoscopic resection for CRC between January 2008 and September 2013 was performed. Results: Three hundred seventy-one patients had open and 110 had laparoscopic resections. There was no difference between open 17.85) and laparoscopic 18.91) approaches p = 0.171) in the number of lymph nodes harvested. Patients who had more nodes removed tended toward improved survival, independent of stage p = 0.052), an effect that was more pronounced in the open resection group p = 0.031). There was no difference in survival between the open and laparoscopic groups overall HR 1.52, p = 0.208). Discussion: No survival advantage was found between the open and laparoscopic resection groups, affirming that the choice of operative approach for CRC does not affect the quality of the oncologic procedure in a community hospital setting. Patients who had more lymph nodes removed tended toward improved survival. The explanation for this effect remains unclear. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:926 / 930
页数:5
相关论文
共 20 条
[1]  
Agarwal Samir, 2015, Proc (Bayl Univ Med Cent), V28, P296
[2]  
[Anonymous], 2005, GUID LAP RES CUR COL
[3]  
Bonjer HJ, 2007, ARCH SURG-CHICAGO, V142, P298
[4]   Laparoscopy as a prognostic factor in curative resection for node positive colorectal cancer - Results for a single-institution nonrandomized prospective trial [J].
Capussotti, L ;
Massucco, P ;
Muratore, A ;
Amisano, M ;
Bima, C ;
Zorzi, D .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2004, 18 (07) :1130-1135
[5]   The optimal number of lymph nodes examined in stage II colorectal cancer and its impact of on outcomes [J].
Choi, Hok Kwok ;
Law, Wai Lun ;
Poon, Jensen T. C. .
BMC CANCER, 2010, 10
[6]   Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group Trial [J].
Fleshman, James ;
Sargent, Daniel J. ;
Green, Erin ;
Anvari, Mehran ;
Stryker, Steven J. ;
Beart, Robert W., Jr. ;
Hellinger, Michael ;
Flanagan, Richard, Jr. ;
Peters, Walter ;
Nelson, Heidi .
ANNALS OF SURGERY, 2007, 246 (04) :655-664
[7]  
Horzic M, 2005, HEPATO-GASTROENTEROL, V52, P86
[8]  
Howlader N., 2012, SEER CANC STAT REV, P1975
[9]   Laparoscopic colectomy for colon adenocarcinoma - An 11-year retrospective review with 5-year survival rates [J].
Jacob, BP ;
Salky, B .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2005, 19 (05) :643-649
[10]  
Khan RSA, 2013, BCMJ, P18