07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived xylariaceous fungus LL-07H239

被引:52
作者
McDonald, LA [1 ]
Barbieri, LR [1 ]
Bernan, VS [1 ]
Janso, J [1 ]
Lassota, P [1 ]
Carter, GT [1 ]
机构
[1] Wyeth Ayerst Res, Pearl River, NY 10965 USA
来源
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 09期
关键词
D O I
10.1021/np049924g
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
07H239-A (1), a new eremophilane sesquiterpene from a marine-derived xylariaceous fungus, was isolated, characterized, and shown to be cytotoxic toward a variety of cancer cell lines, with some selectivity for a CCRFCEM leukemia line (IC50 = 0.9 mug/mL).
引用
收藏
页码:1565 / 1567
页数:3
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