Utility of TICS-M for the assessment of cognitive function in older adults

被引:348
作者
de Jager, CA
Budge, MM
Clarke, R
机构
[1] Radcliffe Infirm Trust, OPTIMA, Oxford OX2 6HE, England
[2] Univ Oxford, Dept Pharmacol, Oxford OX1 3QT, England
[3] Radcliffe Infirm, Clin Trial Serv Unit, Oxford OX2 6HE, England
关键词
TICS-M; telephone screening; dementia; Alzheimer's disease; MMSE; CAMCOG; memory; cognitive;
D O I
10.1002/gps.830
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background Routine screening of high-risk elderly people for early cognitive impairment is constrained by the limitations of currently available cognitive function tests. The Telephone Interview, of Cognitive Status is a novel instrument for assessment of cognitive function that can be administered in person or by telephone. Objective To evaluate the determinants and Utility of TICS-M (13-item modified version) for assessment of cognitive function in healthy elderly people. Methods The utility of TICS-M vas compared with more widely used MMSE and CAMCOG in a cross-sectional survey of 120 older (62 to 89 years) UK adults. Results The TICS-M cognitive test scores (27.97. SID 4.15) were normally distributed in contrast with those for MMSE and CAMCOG that had a negatively skewed distribution. TICS-M scores were inversely correlated with age (r = -0.21) and with the NART fullscale IQ (r = -0.35), but were independent of years of education in this cohort. TICS-M was highly correlated with MMSE (r = 0.57) and with CAMCOG (r = 0.62) scores. The time required to complete the test is comparable to MMSE and substantially less than CAMCOG. Conclusions The normal distribution of TICS-M test scores suggest that this test is less constrained by the ceiling effect which limits the utility of MMSE and CAMCOG test scores in detecting early cognitive impairment. TICS-M is an appropriate instrument to assess cognitive function in both research and in clinical practice. Copyright (C) 2003 John Wiley Sons, Ltd.
引用
收藏
页码:318 / 324
页数:7
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