Bioavailability, metabolism and physiological impact of 4-oxo-flavonoids

被引：180

作者：

Manach, C

Regerat, F

Texier, O

Agullo, G

Demigne, C

Remesy, C

机构：

[1] INRA,MALAD METAB LAB,F-63122 ST GENES CHAMPANE,FRANCE

[2] FAC PHARM CLERMONT FERRAND,LAB PHARMACOGNOSIE & BIOTECHNOL,F-63001 CLERMONT FERRAND,FRANCE

来源：

NUTRITION RESEARCH | 1996年 / 16卷 / 03期

关键词：

4-oxo-flavonoids; quercetin; antioxidant; cardiovascular diseases; antitumoral effect; carcinogenicity;

D O I：

10.1016/0271-5317(96)00032-2

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

4-oxo-flavonoids are dietary compounds widely distributed in the plant kingdom. Interest in these substances has arisen because of possible effects on human health. Indeed, in spite of extensive metabolism by the intestinal flora, 4-oxo-flavonoids seem to be sufficiently absorbed to have physiological effects. This review discusses the possibilities of a positive role in cardiovascular disease and cancer prevention, particularly by their antioxidant properties and their ability to modulate the activity of many enzymes, and summarizes the data concerning an eventual carcinogenicity of 4-oxo-flavonoids.

引用

页码：517 / 544

页数：28

共 180 条

[1] CHELATING AND FREE-RADICAL SCAVENGING MECHANISMS OF INHIBITORY-ACTION OF RUTIN AND QUERCETIN IN LIPID-PEROXIDATION [J].