Placental development during early pregnancy: Effects of embryo origin on expression of chemokine ligand twelve (CXCL12)

被引：13

作者：

Quinn, K. E. ^{[1
]}

Reynolds, L. P. ^{[2
,3
]}

Grazul-Bilska, A. T. ^{[2
,3
]}

Borowicz, P. P. ^{[2
,3
,4
]}

Ashley, R. L. ^{[1
]}

机构：

[1] New Mexico State Univ, Dept Anim & Range Sci, 2980 South Espina St, Las Cruces, NM 88003 USA

[2] N Dakota State Univ, Ctr Nutr & Pregnancy, Fargo, ND 58108 USA

[3] N Dakota State Univ, Dept Anim Sci, Fargo, ND 58108 USA

[4] N Dakota State Univ, Dept 7630, Adv Imaging & Microscopy Core Lab, Fargo, ND 58108 USA

来源：

PLACENTA | 2016年 / 43卷

基金：

美国食品与农业研究所;

关键词：

CXCL12; Implantation; Placentation; Assisted reproductive technologies; SHEEP; IMPLANTATION; GROWTH; FETAL; ANGIOGENESIS; TROPHOBLASTS; OSTEOPONTIN; CATTLE; CELLS; CD82;

D O I：

10.1016/j.placenta.2016.05.008

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The aim was to localize chemokine ligand twelve (CXCL12) in sheep placental tissues during early gestation and after assisted reproductive technologies (ART). Uteri were collected from naturally (NAT) mated ewes and ewes receiving embryo transfer (ET), in vitro fertilization (IVF) or in vitro activation (IVA). CXCL12 was immunolocalized to endometrial stroma, glands, and trophoblast. Greater CXCL12 immunoreactivity was present in trophoblast on day 22 and 24 and in NAT ewes compared to IVF and IVA. Increased CXCL12 expression suggests CXCL12 promotes implantation and placentation. Decreased CXCL12 in IVF and IVA embryos, may compromise pregnancy establishment when utilizing ART methods. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：77 / 80

页数：4

共 23 条

[21] Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1 [J].

Salvucci, O ;

Yao, L ;

Villalba, S ;

Sajewicz, A ;

Pittaluga, S ;

Tosato, G .

BLOOD, 2002, 99 (08) :2703-2711

[22]

Schindelin J, 2012, NAT METHODS, V9, P676, DOI [10.1038/nmeth.2019, 10.1038/NMETH.2019]

[23] ROLE OF BINUCLEATE CELLS IN FETOMATERNAL CELL-FUSION AT IMPLANTATION IN THE SHEEP [J].

WOODING, FBP .

AMERICAN JOURNAL OF ANATOMY, 1984, 170 (02) :233-250

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