Critical Issues in Food Allergy: A National Academies Consensus Report

被引:69
作者
Sicherer, Scott H. [1 ]
Allen, Katrina [2 ,3 ]
Lack, Gideon [4 ,5 ]
Taylor, Steve L. [6 ]
Donovan, Sharon M. [7 ]
Oria, Maria [8 ]
机构
[1] Icahn Sch Med Mt Sinai, Jaffe Food Allergy Inst, Dept Pediat, Div Pediat Allergy & Immunol, New York, NY 10029 USA
[2] Univ Melbourne, Ctr Food & Allergy Res, Murdoch Childrens Res Inst, Melbourne, Vic, Australia
[3] Univ Manchester, Inst Inflammat & Repair, Manchester, Lancs, England
[4] Kings Coll London, Dept Paediat Allergy, Div Asthma Allergy & Lung Biol, London, England
[5] Guys & St Thomas NHS Fdn Trust, London, England
[6] Univ Nebraska, Dept Food Sci & Technol, Food Allergy Res & Resource Program, Lincoln, NE 68583 USA
[7] Univ Illinois, Dept Food Sci & Human Nutr, Urbana, IL 61801 USA
[8] Natl Acad Sci Engn & Med, Washington, DC USA
基金
美国国家卫生研究院; 美国食品与农业研究所;
关键词
NATURAL-HISTORY; ANAPHYLAXIS GUIDELINES; EUROPEAN ACADEMY; PEANUT ALLERGY; CHILDREN; MANAGEMENT; PREVALENCE; CHALLENGES; PREVENTION; DIAGNOSIS;
D O I
10.1542/peds.2017-0194
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The National Academies of Sciences, Engineering, and Medicine convened an expert, ad hoc committee to examine critical issues related to food allergy. The authors of the resulting report, "Finding a Path to Safety in Food Allergy: Assessment of the Global Burden, Causes, Prevention, Management, and Public Policy, "evaluated the scientific evidence on the prevalence, diagnosis, prevention, and management of food allergy and made recommendations to bring about a safe environment for those affected. The committee recommended approaches to monitor prevalence, explore risk factors, improve diagnosis, and provide evidence-based health care. Regarding diagnostics, emphasis was placed on utilizing allergy tests judiciously in the context of the medical history because positive test results are not, in isolation, diagnostic. Evidence-based prevention strategies were advised (for example, a strategy to prevent peanut allergy through early dietary introduction). The report encourages improved education of stakeholders for recognizing and managing as well as preventing allergic reactions, including an emphasis on using intramuscular epinephrine promptly to treat anaphylaxis. The report recommends improved food allergen labeling and evaluation of the need for epinephrine autoinjectors with a dosage appropriate for infants. The committee recommended policies and guidelines to prevent and treat food allergic reactions in a various settings and suggested research priorities to address key questions about diagnostics, mechanisms, risk determinants, and management. Identifying safe and effective therapies is the ultimate goal. This article summarizes the key findings from the report and emphasizes recommendations for actions that are applicable to pediatricians and to the American Academy of Pediatrics.
引用
收藏
页数:8
相关论文
共 39 条
[1]   Prospects for Prevention of Food Allergy [J].
Allen, Katrina J. ;
Koplin, Jennifer J. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2016, 4 (02) :215-220
[2]   Longitudinal evaluation of food allergy-related bullying [J].
Annunziato, Rachel A. ;
Rubes, Melissa ;
Ambrose, Michael A. ;
Mullarkey, Chloe ;
Shemesh, Eyal ;
Sicherer, Scott H. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2014, 2 (05) :639-641
[4]  
BOCK SA, 1987, PEDIATRICS, V79, P683
[5]   Food Allergy Among Children in the United States [J].
Branum, Amy M. ;
Lukacs, Susan L. .
PEDIATRICS, 2009, 124 (06) :1549-1555
[6]   NIAID-Sponsored 2010 Guidelines for Managing Food Allergy: Applications in the Pediatric Population [J].
Burks, A. Wesley ;
Jones, Stacie M. ;
Boyce, Joshua A. ;
Sicherer, Scott H. ;
Wood, Robert A. ;
Assa'ad, Amal ;
Sampson, Hugh A. .
PEDIATRICS, 2011, 128 (05) :955-965
[7]   Epinephrine in Anaphylaxis: Higher Risk of Cardiovascular Complications and Overdose After Administration of Intravenous Bolus Epinephrine Compared with Intramuscular Epinephrine [J].
Campbell, Ronna L. ;
Bellolio, Fernanda ;
Knutson, Benjamin D. ;
Bellamkonda, Venkatesh R. ;
Fedko, Martin G. ;
Nestler, David M. ;
Hess, Erik P. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2015, 3 (01) :76-80
[8]   Diagnosing and Managing Common Food Allergies A Systematic Review [J].
Chafen, Jennifer J. Schneider ;
Newberry, Sydne J. ;
Riedl, Marc A. ;
Bravata, Dena M. ;
Maglione, Margaret ;
Suttorp, Marika J. ;
Sundaram, Vandana ;
Paige, Neil M. ;
Towfigh, Ali ;
Hulley, Benjamin J. ;
Shekelle, Paul G. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 303 (18) :1848-1856
[9]   Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants [J].
Fleischer, David M. ;
Sicherer, Scott ;
Greenhawt, Matthew ;
Campbell, Dianne ;
Chan, Edmond ;
Muraro, Antonella ;
Halken, Susanne ;
Katz, Yitzhak ;
Ebisawa, Motohiro ;
Eichenfield, Lawrence ;
Sampson, Hugh ;
Lack, Gideon ;
Du Toit, George ;
Roberts, Graham ;
Bahnson, Henry ;
Feeney, Mary ;
Hourihane, Jonathan ;
Spergel, Jonathan ;
Young, Michael ;
As'aad, Amal ;
Allen, Katrina ;
Prescott, Susan ;
Kapur, Sandeep ;
Saito, Hirohisa ;
Agache, Ioana ;
Akdis, Cezmi A. ;
Arshad, Hasan ;
Beyer, Kirsten ;
Dubois, Anthony ;
Eigenmann, Philippe ;
Fernandez-Rivas, Monserrat ;
Grimshaw, Kate ;
Hoffman-Sommergruber, Karin ;
Host, Arne ;
Lau, Susanne ;
O'Mahony, Liam ;
Mills, Clare ;
Papadopoulos, Nikolaus ;
Venter, Carina ;
Agmon-Levin, Nancy ;
Kessel, Aaron ;
Antaya, Richard ;
Drolet, Beth ;
Rosenwasser, Lanny .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 136 (02) :258-261
[10]   Oral Food Challenges in Children with a Diagnosis of Food Allergy [J].
Fleischer, David M. ;
Bock, S. Allan ;
Spears, Gayle C. ;
Wilson, Carla G. ;
Miyazawa, Naomi K. ;
Gleason, Melanie C. ;
Gyorkos, Elizabeth A. ;
Murphy, James R. ;
Atkins, Dan ;
Leung, Donald Y. M. .
JOURNAL OF PEDIATRICS, 2011, 158 (04) :578-U82