Predictive Independent Factors for Extrahepatic Metastasis of Hepatocellular Carcinoma Following Curative Hepatectomy

被引：17
作者：
Hashimoto, Masakazu [1 ]
Kobayashi, Tsuyoshi [1 ]
Ishiyama, Kohei [1 ]
Ide, Kentaro [1 ]
Ohira, Masahiro [1 ]
Tahara, Hiroyuki [1 ]
Kuroda, Shintaro [1 ]
Hamaoka, Michinori [1 ]
Iwako, Hiroshi [1 ]
Okimoto, Sho [1 ]
Honmyo, Naruhiko [1 ]
Ohdan, Hideki [1 ]
机构：
[1] Hiroshima Univ, Dept Gastroenterol & Transplant Surg, Appl Life Sci, Inst Biomed & Hlth Sci, Hiroshima, Japan
来源：
ANTICANCER RESEARCH | 2017年 / 37卷 / 05期
关键词：
Hepatocellular carcinoma; surgical resection; prognosis; extrahepatic recurrence; intrahepatic recurrence; ARTERIAL INFUSION CHEMOTHERAPY; RISK-FACTORS; INTRAHEPATIC RECURRENCE; SURGICAL COMPLICATIONS; RESECTION; CLASSIFICATION; SORAFENIB; PATTERNS; ADJUVANT; CELLS;
D O I：
10.21873/anticanres.11609
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Aim: The aim of this study was to investigate the prognostic factors associated with extrahepatic metastasis of primary hepatocellular carcinoma (HCC). Patients and Methods: We retrospectively analyzed 559 patients with HCC who underwent curative hepatectomy. We divided the patients into no recurrence (NoR), intrahepatic early recurrence (IHER), intrahepatic late recurrence (IHLR), and extrahepatic recurrence (EHR) groups. We compared the non-metastatic group (IHLR and NoR) with the metastatic group (IHER and EHR) and also compared IHER with EHR to determine risk factors for EHR. Results: There were 252, 163, 109, and 35 patients with NoR, IHER, IHLR, and EHR, respectively. For the EHR group, the independent risk factor was vascular invasion. The EHR group had better liver function and worse tumor factors. Conclusion: Vascular invasion is predictive of extrahepatic metastasis of HCC.
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收藏
页码：2625 / 2631
页数：7
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