Solution-phase parallel synthesis of benzoxazines using a polymer-supported carbodiimide

被引：15
|
作者：
Buckman, BO [1 ]
Morrissey, MM [1 ]
Mohan, R [1 ]
机构：
[1] Berlex Biosci, Pharmaceut Discovery, Richmond, CA 94804 USA
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 12期
关键词：
D O I：
10.1016/S0040-4039(98)00012-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A diverse library of 2-aminobenzoxazines 3 has been synthesized using a two step approach. Addition of anthranilic acids to isocyanates affords ureas 2 that can be cyclized by polymer-supported EDC to give 2-aminobenzoxazines 3. (C) 1998 Elsevier Science Ltd. All rights reserved.
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收藏
页码：1487 / 1488
页数：2
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