Synthesis, dehydration and oxidation of 3-cyano-4,6-diaryl-5-ethoxycarbonyl-6-hydroxypiperidine-2-thiones

被引：0
作者：
Krauze, A [1 ]
Duburs, G [1 ]
机构：
[1] Latvian Inst Organ Synth, LV-1006 Riga, Latvia
来源：
HETEROCYCLIC COMMUNICATIONS | 2000年 / 6卷 / 03期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
6-Hydroxypiperidine-2-thiones 2 and 1,4-dihydropyridine-2(3H)-thiones (3) under bar were obtained by an unsymmetrical condensation of ethyl 4-nitrobenzoylacetate, an aromatic aldehyde and cyanothioacetamide in the presence of piperidine with subsequent acidification. Oxidation of piperidine-2-thiones (2) under bar with iodine yielded 2,2'-bis(1,4,5,6-tetrahydropyridyl)disulfides (4) under bar. 2,2'-Bis(1,4-dihydropyridyl)disulfides (5) under bar were obtained by treatment of (1) under bar or (4) under bar with hydrochloric acid, or by oxidation of 1,4-dihydropyridine-2(3H)thiones (3) under bar with iodine.
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页码：239 / 244
页数：6
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