Imagery rescripting and eye movement desensitisation and reprocessing for treatment of adults with childhood trauma-related post-traumatic stress disorder: IREM study design

被引：31

作者：

de Haan, Katrina L. Boterhoven ^{[1
]}

Lee, Christopher W. ^{[1
]}

Fassbinder, Eva ^{[2
]}

Voncken, Marisol J. ^{[3
]}

Meewisse, Mariel ^{[4
]}

Van Es, Saskia M. ^{[5
]}

Menninga, Simone ^{[6
]}

Kousemaker, Margriet ^{[7
]}

Arntz, Arnoud ^{[8
]}

机构：

[1] Univ Western Australia, UWA Med Sch, Fac Hlth & Med Sci, Div Psychiat, 35 Stirling Highway, Crawley, WA 6009, Australia

[2] Lubeck Univ, Sch Psychiat, Ratzeburger Allee 160, D-23562 Lubeck, Germany

[3] Maastricht Univ, Fac Psychol & Neurosci, Dept Clin Psychol Sci, POB 616, NL-6200 MD Maastricht, Netherlands

[4] GGZ Noord Holland Noord, Stationspl 138, NL-1703 WC Heerhugowaard, Netherlands

[5] PsyQ Amsterdam, George Westinghousestr 2, NL-1097 BA Amsterdam, Netherlands

[6] PsyQ Beverwijk, Leeghwaterweg 1A, NL-1097 BA Velsen Noord, Netherlands

[7] Sinai Ctr, Laan van de Helende Meesters 2,Postbus 2063, NL-1180 EB Amstelveen, Netherlands

[8] Univ Amsterdam, Dept Clin Psychol, Weesperpl 4, NL-1018 XA Amsterdam, Netherlands

来源：

BMC PSYCHIATRY | 2017年 / 17卷

关键词：

Post-traumatic stress disorder; Childhood; Imagery rescripting; Eye movement desensitisation and reprocessing; Treatment; COGNITIVE-BEHAVIORAL THERAPY; COMPLEX PTSD; RESOURCE DEVELOPMENT; EXPOSURE THERAPY; FEMALE SURVIVORS; SEXUAL-ABUSE; EMDR; EFFICACY; MEMORIES; INTERVENTION;

D O I：

10.1186/s12888-017-1330-2

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Background: Post-traumatic stress disorder (PTSD) that originates from childhood trauma experiences can develop into a chronic condition that has lasting effects on an individual's functioning and quality of life. While there are evidence-based guidelines for treating adult onset PTSD, treatments for adults with childhood trauma-related PTSD (Ch-PTSD) are varied and subject to ongoing debate. This study will test the effectiveness of two trauma-focused treatments, imagery rescripting (ImRs) and eye movement desensitisation and reprocessing (EMDR) in participants with Ch-PTSD. Both have been found effective in treatment of adult PTSD or mixed onset PTSD and previous research indicates they are well-tolerated treatments. However, we know less about their effectiveness for treating Ch-PTSD or their underlying working mechanisms. Methods: IREM is an international multicentre randomised controlled trial involving seven sites across Australia, Germany and the Netherlands. We aim to recruit 142 participants (minimum of n = 20 per site), who will be randomly assigned to treatment condition. Assessments will be conducted before treatment until 1-year follow-up. Assessments before and after the waitlist will assess change in time only. The primary outcome measure is change in PTSD symptom severity from pre-treatment to 8-weeks post-treatment. Secondary outcome measures include change in severity of depression, anger, trauma-related cognitions, guilt, shame, dissociation and quality of life. Underlying mechanisms of treatment will be assessed on changes in vividness, valence and encapsulated belief of a worst trauma memory. Additional sub-studies will include qualitative investigation of treatment experiences from the participant and therapists' perspective, changes in memory and the impact of treatment fidelity on outcome measures. Discussion: The primary aims of this study are to compare the effectiveness of EMDR and ImRs in treating Ch-PTSD and to investigate the underlying working mechanisms of the two treatments. The large-scale international design will make a significant contribution to our understanding of how these treatments address the needs of individuals with Ch-PTSD and therefore, potentially improve their effectiveness.

引用

页数：12

共 64 条

[1] Eye-movements and visual imagery: A working memory approach to the treatment of post-traumatic stress disorder [J].