Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification

被引：772
|
作者：
Hoshino, A
Fujioka, K
Oku, T
Suga, M
Sasaki, YF
Ohta, T
Yasuhara, M
Suzuki, K
Yamamoto, K
机构：
[1] Int Med Ctr Japan, Dept Med Ecol & Informat, Tokyo 1628655, Japan
[2] Tokyo Med & Dent Univ, Grad Sch, Hosp Pharm, Dept Pharmacokinet & Pharmacodynam,Bunkyo Ku, Tokyo 1138519, Japan
[3] Natl Inst Infect Dis, Dept Bioact Mol, Tokyo 1628640, Japan
[4] Hachinohe Inst Technol, Fac Chem & Biol Engn, Hachinohe, Aomori 0391192, Japan
[5] Tokyo Univ Pharm & Life Sci, Sch Life Sci, Hachioji, Tokyo 1920392, Japan
来源：
NANO LETTERS | 2004年 / 4卷 / 11期
关键词：
D O I：
10.1021/nl048715d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Nanocrystal quantum dots (QDs) have been applied to molecular biology because of their greater and longer fluorescence. Here we report the potential cytotoxicity of our characterized QDs modified with various molecules. Surface modification of QDs changed their physicochemical properties. In addition, the cytotoxicity of QDs was dependent on their surface molecules. These results suggested that the properties of QDs are not related to those of QD-core materials but to molecules covering the surface of QDs.
引用
收藏
页码：2163 / 2169
页数：7
相关论文
共 50 条
  • [1] Cellular Interaction and Toxicity Depend on Physicochemical Properties and Surface Modification of Redox-Active Nanomaterials
    Dowding, Janet M.
    Das, Soumen
    Kumar, Amit
    Dosani, Talib
    McCormack, Rameech
    Gupta, Ankur
    Sayle, Thi X. T.
    Sayle, Dean C.
    von Kalm, Laurence
    Seal, Sudipta
    Self, William T.
    ACS NANO, 2013, 7 (06) : 4855 - 4868
  • [2] Toxicity of nanocrystal quantum dots: the relevance of surface modifications
    Hoshino, Akiyoshi
    Hanada, Sanshiro
    Yamamoto, Kenji
    ARCHIVES OF TOXICOLOGY, 2011, 85 (07) : 707 - 720
  • [3] Toxicity of nanocrystal quantum dots: the relevance of surface modifications
    Akiyoshi Hoshino
    Sanshiro Hanada
    Kenji Yamamoto
    Archives of Toxicology, 2011, 85
  • [4] Erratum to: Toxicity of nanocrystal quantum dots: the relevance of surface modifications
    Akiyoshi Hoshino
    Sanshiro Hanada
    Kenji Yamamoto
    Archives of Toxicology, 2011, 85 (7)
  • [5] Physicochemical properties and cellular toxicity of (poly)aminoalkoxysilanes-functionalized ZnO quantum dots
    Aboulaich, Abdelhay
    Tilmaciu, Carmen-Mihaela
    Merlin, Christophe
    Mercier, Cedric
    Guilloteau, Helene
    Medjahdi, Ghouti
    Schneider, Raphael
    NANOTECHNOLOGY, 2012, 23 (33)
  • [6] Toxicity evaluation of cadmium-containing quantum dots: A review of optimizing physicochemical properties to diminish toxicity
    Hu, Liang
    Zhong, Hui
    He, Zhiguo
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2021, 200
  • [7] Effect of surface modification on optical and electronic properties of graphene quantum dots
    Rani, Priya
    Dalal, Ranjeet
    Srivastava, Sunita
    APPLIED SURFACE SCIENCE, 2023, 609
  • [8] Regulation of physicochemical characteristics on surface of SiC quantum dots and its optical properties
    Kang, Jie
    Song, Yuepeng
    Zhu, Yanmin
    Gao, Dongsheng
    Guo, Jing
    Xu, Lingfeng
    Kim, Hyoungseop
    Kuei Suan Jen Hsueh Pao/Journal of the Chinese Ceramic Society, 2015, 43 (04): : 431 - 436
  • [9] Revisiting the principles of preparing aqueous quantum dots for biological applications: the effects of surface ligands on the physicochemical properties of quantum dots
    Zhang, Butian
    Hu, Rui
    Wang, Yucheng
    Yang, Chengbin
    Liu, Xin
    Yong, Ken-Tye
    RSC ADVANCES, 2014, 4 (27) : 13805 - 13816
  • [10] Optical properties of PbSe nanocrystal quantum dots under pressure
    Zhuravlev, Kirill K.
    Pietryga, Jeffrey M.
    Sander, Robert K.
    Schaller, Richard D.
    APPLIED PHYSICS LETTERS, 2007, 90 (04)
12345