A practical approach to guideline-directed pharmacological treatment for heart failure with reduced ejection fraction

被引:0
|
作者
Soltani, Samira [1 ]
Boehm, Michael [2 ]
Frey, Norbert [3 ]
Eden, Matthias [3 ]
Abdin, Amr [2 ]
Bauersachs, Johann [1 ]
机构
[1] Hannover Med Sch, Klin Kardiol & Angiol, Carl Neuberg Str 1, D-30625 Hannover, Germany
[2] Univ Klin Saarlandes, Klin Innere Med Kardiol Angiol & Intemist Intens, Homburg, Germany
[3] Univ Klinikum Heidelberg, Klin Kardiol Angiol & Pneumol, Heidelberg, Germany
关键词
heart failure; guideline-compliant drug therapy; HFrEF; SPIRONOLACTONE; EPLERENONE; BLOCKER;
D O I
10.1055/a-1760-3843
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The 2021 guidelines of the European Society of Cardiology for the diagnosis and treatment of heart failure recommend the early implementation of all four mortality-lowering drug classes for heart failure with reduced ejection fraction (HFrEF), i. e. angiotensin-converting enzyme inhibitor (ACEi) or angiotensin receptor II blocker-neprilysin inhibitor (ARNI), betablocker (BB), mineralocorticoid receptor-antagonists (MRA), and sodium-glucose linked transporter-2 inhibitors (SGLT2i). This article aims to give a practical compendium supporting physicians to enable safe and efficacious treatment for patients with HFrEF.
引用
收藏
页码:931 / 938
页数:8
相关论文
共 50 条
  • [31] Initiation and sequencing of guideline-directed medical therapy for heart failure across the ejection fraction spectrum
    Shahid, Izza
    Khan, Muhammad Shahzeb
    Butler, Javed
    Fonarow, Gregg C.
    Greene, Stephen J.
    HEART FAILURE REVIEWS, 2025, : 515 - 523
  • [32] Practical Pharmacological Treatment of Heart Failure: Does Ejection Fraction Matter Anymore?
    Chan, Jonathan C. H.
    Cowley, Emily
    Chan, Michael
    JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE, 2023, 10 (03)
  • [33] Navigating between Scylla and Charybdis: challenges and strategies for implementing guideline-directed medical therapy in heart failure with reduced ejection fraction
    Seferovic, Petar M.
    Polovina, Marija
    Adlbrecht, Christopher
    Belohlavek, Jan
    Chioncel, Ovidiu
    Goncalvesova, Eva
    Milinkovic, Ivan
    Grupper, Avishay
    Halmosi, Robert
    Kamzola, Ginta
    Koskinas, Konstantinos C.
    Lopatin, Yuri
    Parkhomenko, Alexander
    Poder, Pentti
    Ristic, Arsen D.
    Sakalyte, Gintare
    Trbusic, Matias
    Tundybayeva, Meiramgul
    Vrtovec, Bojan
    Yotov, Yoto T.
    Milicic, Davor
    Ponikowski, Piotr
    Metra, Marco
    Rosano, Giuseppe
    Coats, Andrew J. S.
    EUROPEAN JOURNAL OF HEART FAILURE, 2021, 23 (12) : 1999 - 2007
  • [34] Use and Intensi fi cation of Oral Guideline-Directed Medical Therapy in Hospitalized Patients With Heart Failure and Reduced Ejection Fraction
    Hocutt, Benajamin
    Owen, Melissa
    Albert, Nancy M.
    JNP- THE JOURNAL FOR NURSE PRACTITIONERS, 2024, 20 (07):
  • [35] Utilization of guideline-directed medical therapy in patients with de novo heart failure with reduced ejection fraction: A Veterans Affairs study
    Khattab, Mohamad
    Parwani, Purvi
    Abbas, Mubasher
    Ali, Huzair
    Lozano, Pedro M.
    Thadani, Udho
    Dasari, Tarun W.
    JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE, 2020, 9 (06) : 3065 - 3069
  • [36] Effect of Guideline-Directed Medical Therapy on Central Aortic Pressure Waveforms in Patients With Heart Failure With Reduced Ejection Fraction.
    Morris, Alanna A.
    Chen, Christopher
    Udeshi, Eisha
    Butler, Javed
    Quyyumi, Arshed
    CIRCULATION, 2018, 138
  • [37] Pharmacy-Led Optimization of Guideline-Directed Medical Therapy in Heart Failure With Reduced Ejection Fraction Program Improves Heart Failure Metrics in a Safety-Net Hospital
    Barbera, Gabrielle
    Norman, Kelsey
    Lee, Meissane
    Jones, Kyle
    Pipilas, Alexandra
    Wulff, Kelly
    Surjanhata, Alana
    Paul, Ludwine
    Ahluwalia, Monica
    Nayor, Matthew G.
    Gopal, Deepa M.
    CIRCULATION, 2023, 148
  • [38] Rationale and design of a navigator-driven remote optimization of guideline-directed medical therapy in patients with heart failure with reduced ejection fraction
    Blood, Alexander J.
    Fischer, Christina M.
    Fera, Liliana E.
    MacLean, Taylor E.
    Smith, Katelyn, V
    Dunning, Jacqueline R.
    Bosque-Hamilton, Joshua W.
    Aronson, Samuel J.
    Gaziano, Thomas A.
    MacRae, Calum A.
    Matta, Lina S.
    Mercurio-Pinto, Ana A.
    Murphy, Shawn N.
    Scirica, Benjamin M.
    Wagholikar, Kavishwar
    Desai, Akshay S.
    CLINICAL CARDIOLOGY, 2020, 43 (01) : 4 - 13
  • [39] Analysis of Physician Compliance with Guideline-Directed Medical Therapy for Patients with Heart Failure with Reduced Ejection Fraction: A Real-World Study
    Wang, Guixia
    Liu, Liming
    Wang, Xiaobo
    Yu, Ting
    Xu, Hui
    Zhang, Tingjun
    Lin, Jiafu
    Luo, Hao
    Liu, Yanxu
    Jiang, Lanxiang
    Hu, Wenlong
    Hu, Houxiang
    REVIEWS IN CARDIOVASCULAR MEDICINE, 2023, 24 (09)
  • [40] The independent reduction inmortality associated with guideline-directed medical therapy in patients with coronary artery disease and heart failure with reduced ejection fraction
    Wolfe, Natasha K.
    Mitchell, Joshua D.
    Brown, David L.
    EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES, 2021, 7 (04) : 416 - 421