New clinical protocol to study patients with knee osteoarthritis and psoriasis treated with chondroitin sulfate

被引:0
作者
Perez, M. [1 ]
Dalmau, J. [1 ]
Roe, E. [1 ]
Moller, L. [2 ]
Moragues, C. [2 ]
Marti, N. [2 ]
Benito, P. [3 ]
Monfort, J. [3 ]
Segales, N. [3 ]
Coll, M. [3 ]
Cuevas, J. [4 ]
Perna, C. [4 ]
Herrero, M. [5 ]
Montell, E. [5 ]
Verges, J. [5 ]
机构
[1] Hosp Santa Creu & Sant Pau, Dept Dermatol, Barcelona, Spain
[2] Inst Poal Reumatol, Barcelona, Spain
[3] Hosp del Mar, Dept Rheumatol, Barcelona, Spain
[4] Hosp Gen Univ Guadalajara, Dept Pathol, Guadalajara, Spain
[5] Bioiber Farma, Dept Med Sci, Clin Res Unit, Barcelona, Spain
来源
EADV: PROCEEDINGS OF THE 15TH CONGRESS OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2006年
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中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
After prescribing chondroitin sulfate (CS) for the treatment of osteoarthritis (OA), it was observed that patients with concomitant psoriasis (Ps) experienced a marked improvement of the psoriatic lesions(1-2). In view of this encouraging results and since NSAIDs, often used in the management of OA, have been reported to precipitate or to exacerbate preexisting Ps(3) we designed a clinical trial to evaluate the efficacy and safety of CS in patients with both Ps and knee OA. The obtaining of positive results in the study, which protocol here we describe, could represent an important advance in the therapeutic armamentarium given the excellent safety profile of CS and the possibility to make up for the lack of treatment in patients with both pathologies.
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页码:749 / +
页数:3
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