Identification of novel interactors of human telomeric G-quadruplex DNA

被引：32

作者：

Pagano, Bruno ^{[1
]}

Margarucci, Luigi ^{[2
]}

Zizza, Pasquale ^{[3
]}

Amato, Jussara ^{[1
]}

Iaccarino, Nunzia ^{[1
]}

Cassiano, Chiara ^{[2
]}

Salvati, Erica ^{[3
]}

Novellino, Ettore ^{[1
]}

Biroccio, Annamaria ^{[3
]}

Casapullo, Agostino ^{[2
]}

Randazzo, Antonio ^{[1
]}

机构：

[1] Univ Naples Federico II, Dept Pharm, I-80131 Naples, Italy

[2] Univ Salerno, Dept Pharm, I-84084 Fisciano, SA, Italy

[3] Regina Elena Inst Canc Res, Expt Chemotherapy Lab, I-00158 Rome, Italy

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 14期

关键词：

SECONDARY STRUCTURES; HUMAN-CHROMOSOMES; PROTEIN; PROMOTER; POLYMORPHISM; EXTENSION; SEQUENCE; END;

D O I：

10.1039/c4cc07231f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A chemoproteomic-driven approach was used to investigate the interaction network between human telomeric G-quadruplex DNA and nuclear proteins. We identified novel G-quadruplex binding partners, able to recognize these DNA structures at chromosome ends, suggesting a possible, and so far unknown, role of these proteins in telomere functions.

引用

页码：2964 / 2967

页数：4

共 50 条

[21] Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA
Zhao, Andong
Howson, Suzanne E.
Zhao, Chuanqi
Ren, Jinsong
Scott, Peter
Wang, Chunyu
Qu, Xiaogang
NUCLEIC ACIDS RESEARCH, 2017, 45 (09) : 5026 - 5035
[22] G-quadruplex is in human DNA
Chemical and Engineering News, 2002, 80 (35):
[23] Selective binding of a heterocyclic diamidine compound with human telomeric G-quadruplex DNA
White, Elizabeth W.
Nanjunda, Rupesh K.
Kumar, Arvind
Ismail, Mohamed A.
Boykin, David W.
Wilson, W. David
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
[24] Human Telomeric DNA Sequence-Specific Cleaving by G-Quadruplex Formation
Xu, Yan
Suzuki, Yuta
Loennberg, Tuomas
Komiyama, Makoto
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (08) : 2871 - 2874
[25] Folding and Unfolding Pathways of the Human Telomeric G-Quadruplex
Gray, Robert D.
Trent, John O.
Chaires, Jonathan B.
JOURNAL OF MOLECULAR BIOLOGY, 2014, 426 (08) : 1629 - 1650
[26] Impact of Oxidative Lesions on the Human Telomeric G-Quadruplex
Bielskute, Stase
Plavec, Janez
Podbevsek, Peter
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (06) : 2594 - 2603
[27] Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures
Lin, Clement
Wu, Guanhui
Wang, Kaibo
Onel, Buket
Sakai, Saburo
Shao, Yong
Yang, Danzhou
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (34) : 10888 - 10893
[28] Amentoflavone as a potential telomeric G-Quadruplex DNA stabilizing agent
Revikumar, Amjesh
GENE REPORTS, 2021, 22
[29] Interaction of synthetic fluoroquinolones with telomeric G-quadruplex DNA.
Rangan, A
Fedoroff, OY
Hurley, LH
CLINICAL CANCER RESEARCH, 1999, 5 : 3852S - 3852S
[30] Structural Dynamics and Polymorphism of Telomeric G-Quadruplex DNA Structures
Kragh, Sofie L.
Preus, Soren
Gudnason, Daniel
Mergny, Jean-Louis
Birkedal, Victoria
BIOPHYSICAL JOURNAL, 2014, 106 (02) : 65A - 65A

← 1 2 3 4 5 →